ArticleJournal of cancer survivorship : research and practice2022
Postoperative quality of life and therapy-related impairments of oral cancer in relation to time-distance since treatment.
Article in Journal of cancer survivorship : research and practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of AI-Based Physiotherapy on Mandibular Mobility, Shoulder Function, Whole-Body Physical Function, and Quality of Life in Oral Cancer Patients
Effects of AI Based Physiotherapy on Mandibular Mobility Shoulder Function Whole Body Physical Function Quality of Life and Return to Work in Oral Cancer Patients: 3- and 9-Month Postintervention Follow-Up
Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- Effect of a Home-Based Exercise Program on Muscle Mass, Fatigue, and Health-Related Quality of Life Among Patients with Oral Cancer: A Randomized Trial.Head & neck · 2026Trial
- Concurrent validity and reliability of an artificial intelligence-assisted physiotherapy assessment system for maximal mouth opening, cervical, and shoulder range of motion in patients with oral cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- "When symptoms interact and change": longitudinal network analysis of dynamic symptom changes in oral cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Structural equation modeling of multidimensional determinants of postoperative quality of life in patients with oral cancer.Health and quality of life outcomes · 2026Article
- Dental plaque-inspired peptide engineered to control plaque accumulation.Materials today. Bio · 2025Article
- Predicting postoperative malnutrition in patients with oral cancer: development of an XGBoost model with SHAP analysis and web-based application.Frontiers in oncology · 2025Article
- Article
- Long non-coding RNA PSMG3 Antisense RNA 1 is correlated with oral squamous cell carcinoma and regulates cancer cell proliferation by targeting premature microRNA-141.American journal of cancer research · 2023Article
- Oral functional impairment may cause malnutrition following oral cancer treatment in a single-center cross-sectional study.Scientific reports · 2022Article
- Is There Still a Place for Brachytherapy in the Modern Treatment of Early-Stage Oral Cancer?Cancers · 2022Review
- The relationship between fear of recurrence and depression in patients with cancer: The role of invasive rumination and catastrophizing.Frontiers in psychiatry · 2022Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeOral cancer resection can cause physical and psychological impairments that influence the quality of life (QoL). Depending on the postoperative time-distance, the occurrence and intensity of these impairments may change. We evaluated the sequelae and changes in therapy-related impairments during the postoperative course to detect associations between the time since surgery and the presence of disorders.
methodsData from a questionnaire completed by 1359 patients who underwent surgical treatment of oral squamous cell carcinoma and were involved in a multicenter rehabilitation study of the German-Austrian-Swiss Cooperative Group on Tumors of the Maxillofacial Region (DÖSAK) that included 43 oral and maxillofacial clinics in Germany, Austria, and Switzerland were retrospectively analyzed.
resultsPhysical impairments, including those in appearance, mouth opening ability, ability to smell, gastric disorders, mandible mobility, breathing, and shoulder/arm mobility, were significantly associated with and increased with time-distance since surgery. Esthetic appearance most strongly correlated with the highest perception of worsening. Regarding psychological disorders, worry about tumor recurrence, depression, and worse prospects were significantly associated. Among the postoperative sequelae, fear of tumor recurrence decreased continuously; however, depression and worse prospects increased. The general QoL did not significantly differ overall during the postoperative course.
conclusionsTherapy-related impairments change during the postoperative course based on the time-distance since surgery. The general QoL may not markedly vary; however, single impairments, to some extent, can increase or decrease. IMPLICATIONS FOR CANCER SURVIVORS: Continuous adaptation of supportive cancer therapy is required during follow-up to sufficiently address individual treatment needs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.