ArticleInternational ophthalmology2022
Effect of pseudoexfoliation syndrome on lamina cribrosa morphology after uneventful phacoemulsification.
Article in International ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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3 authors at 1 institution in 1 country.
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Abstract
aimTo evaluate the behavior of the lamina cribrosa (LC) following successful phacoemulsification (PE) surgery in non-glaucomatous PXS cases with cataract.
methodsA total of 25 bilateral PXS and 56 non-PXS cataract patients were included in this prospective, interventional, and controlled study. The lamina cribrosa thickness (LCt) and anterior laminar depth (ALD) were measured horizontally and vertically from two sections using EDI-OCT. The measurements were taken preoperatively, and the LCt and ALD measurements were repeated at week one (W1), month one (M1), month two (M2), and month three (M3) postoperatively.
resultsThe baseline horizontal and vertical LCt values were found to be significantly thinner in the PXS group (p = 0.001, p = 0.006 respectively). The horizontal section ALD values were 463.32 ± 98.82 µm and 383.88 ± 85.8 µm (p < 0.001) for the PXS and non-PXS groups, respectively, and this significance continued during follow-up. The vertical ALD values were 469.64 ± 117.83 µm and 390.3 ± 98.1 µm (p = 0.002) in the PXS and non-PXS groups, respectively. There was no significant change in the PXS group for the depth following PE, but a statistically significant depth increase response was observed in the non-PXS group during follow-up.
conclusionIt is possible to conclude that the bending capacity of the lamina cribrosa may be lower than seen in the normal population, but we do not know how this lack of flexibility will affect the eye.
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