Evidence map›Paper›PMID 34609648›Full record

ArticleEcoHealth2021

Temporal Trends in Antimicrobial Resistance of Fecal Escherichia coli from Deer.

Gregory A Ballash, Lohendy Munoz-Vargas, Amy Albers, Patricia M Dennis, Jeffrey T LeJeune, Dixie F Mollenkopf, Thomas E Wittum

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in EcoHealth, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Characterizing the resistome ofFrontiers in microbiology · 2025
    Article
  3. Article
  4. Article
  5. Effects of EOs vs. Antibiotics onMolecules (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Gregory A BallashDepartment of Veterinary Preventive Medicine, The Ohio State University College of Veterinary Medicine, 1920 Coffey Road, Columbus, OH, 43210, USA.
Lohendy Munoz-VargasDepartment of Veterinary Preventive Medicine, The Ohio State University College of Veterinary Medicine, 1920 Coffey Road, Columbus, OH, 43210, USA.
Amy AlbersDepartment of Veterinary Preventive Medicine, The Ohio State University College of Veterinary Medicine, 1920 Coffey Road, Columbus, OH, 43210, USA.
Patricia M DennisDepartment of Veterinary Preventive Medicine, The Ohio State University College of Veterinary Medicine, 1920 Coffey Road, Columbus, OH, 43210, USA.
Jeffrey T LeJeuneDepartment of Veterinary Preventive Medicine, The Ohio State University College of Veterinary Medicine, 1920 Coffey Road, Columbus, OH, 43210, USA.
Dixie F MollenkopfDepartment of Veterinary Preventive Medicine, The Ohio State University College of Veterinary Medicine, 1920 Coffey Road, Columbus, OH, 43210, USA.
Thomas E WittumDepartment of Veterinary Preventive Medicine, The Ohio State University College of Veterinary Medicine, 1920 Coffey Road, Columbus, OH, 43210, USA. Wittum.1@osu.edu.
The Ohio State University · USCleveland Metroparks Zoo · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The changing epidemiologic role of wildlife as reservoirs of antimicrobial-resistant bacteria (ARB) is poorly understood. In this study, we characterize the phenotypic resistance of commensal Escherichia coli from fecal samples of 879 individual white-tailed (Odocoileus virginianus; WTD) over a ten-year period and analyze resistance patterns. Our results show commensal E. coli from WTD had significant linear increases in reduced susceptibility to 5 of 12 antimicrobials, including broad-spectrum cephalosporins and fluoroquinolones, from 2006 to 2016. In addition, the relative frequency distribution of minimal inhibitory concentrations of two additional antimicrobials shifted towards higher values from across the study period. The prevalence of multidrug-resistant commensal E. coli increased over the study period with a prevalence of 0%, 2.2%, and 3.7% in 2006, 2012, and 2016, respectively. WTD may be persistently and increasingly exposed to antibiotics or their residues, ARB, and/or antimicrobial resistance genes via contaminated environments like surface water receiving treated wastewater effluent.

Indexed as

Anti-Infective AgentsDeerAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsAnimalsAnti-Bacterial AgentsDrug Resistance, BacterialEscherichia coliFecesAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsAnti-Bacterial AgentsAnti-Infective Agentsantimicrobial resistanceEscherichia colitemporal trendswhite-tailed deer

Identifiers

PMID34609648
OpenAlexW3204899833

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.