Evidence map›Paper›PMID 34609608›Full record

ArticleTropical animal health and production2021

Dietary supplementation with Piper sarmentosum extract on gut health of chickens infected with Eimeria tenella.

Fareed Uddin Memon, Yunqiao Yang, Ahmed M Soliman, Feifei Lv, Nasir Rajput, Geyin Zhang, Mirza Baber Baig, Yuhan Wang, Hongbin Si

Abstract readRandomized Controlled Trial, Veterinary
PubMed Publisher
In one paragraph

Article in Tropical animal health and production, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. The Influence ofAnimals : an open access journal from MDPI · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Fareed Uddin MemonDepartment of Clinical Veterinary Medicine, College of Animal Science and Technology, Guangxi University, Nanning, China.
Yunqiao YangDepartment of Clinical Veterinary Medicine, College of Animal Science and Technology, Guangxi University, Nanning, China.
Ahmed M SolimanDepartment of Clinical Veterinary Medicine, College of Animal Science and Technology, Guangxi University, Nanning, China.
Feifei LvDepartment of Clinical Veterinary Medicine, College of Animal Science and Technology, Guangxi University, Nanning, China.
Nasir RajputDepartment of Poultry Husbandry, Faculty of Animal Husbandry and Veterinary Sciences, Sindh Agricultural University, Tando Jam, Pakistan.
Geyin ZhangDepartment of Clinical Veterinary Medicine, College of Animal Science and Technology, Guangxi University, Nanning, China.
Mirza Baber BaigCollage of Electrical Engineering, Guangxi University, Nanning, China.
Yuhan WangDepartment of Clinical Veterinary Medicine, College of Animal Science and Technology, Guangxi University, Nanning, China.
Hongbin SiDepartment of Clinical Veterinary Medicine, College of Animal Science and Technology, Guangxi University, Nanning, China. shb2009@gxu.edu.cn.
Guangxi University · CNAnimal Health Research Institute · TWSindh Agriculture University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To explore the potential alternative of anti-coccidials, we investigated the therapeutic efficacy of dietary Piper sarmentosum extract (PSE) on induced coccidia infection in chickens. A total of 96-day-old chickens were randomly distributed to 1 of 3 treatment groups, including (1) control negative untreated uninfected (CN), (2) control positive untreated infected (CP), and (3) Piper sarmentosum (P. sarmentosum) extract-treated infected group (PSE). Our results demonstrated that E. tenella challenged untreated group showed a reduction (P < 0.05) in post-infection (PI) body weight compared to control negative group. However, supplementation of P. sarmentosum extract had no significant effects on body weight and cecal lesions compared with control positive group. Infected chickens fed PSE diet decreased (P < 0.05) the bloody diarrhea scores and oocyst shedding (during the day 5 to 8 post-infection) than that of CP chickens. E. tenella-challenged chickens upregulated (P < 0.05) the mRNA expression of IL-8 and Bcl-2 compared to PSE chickens, while IFN-γ compared to CN chickens. On the other hand, treatment of P. sarmentosum extract tended to increase (P < 0.05) the transcription patterns of IL-4, IL-10, CLDN 1, SOD 1, and Bax with the comparison of control positive group; however, there were no significant effects on IL-8, ZO 1, and CAT expression between the PSE and CP groups. Collectively, these findings elaborated that dietary P. sarmentosum extract exhibit potential anti-coccidial effects in controlling the coccidia infection in chickens.

Indexed as

CoccidiosisEimeria tenellaPiperPoultry DiseasesAnimalsChickensDietary SupplementsEimeria tenella, chickenGut healthPiper sarmentosum extract

Identifiers

PMID34609608
OpenAlexW3204346038

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.