Evidence map›Paper›PMID 34609426›Full record

ArticleRomanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie

Clinical, histopathological and immunohistochemical features of glomus tumor of the nail bed.

Mihaela Perţea, Vladimir Poroch, Natalia Velenciuc, Mihaela Mitrea, Sorinel Luncă, Cristina Terinte, Alexandru Filip, Ovidiu Alexa, Bogdan Veliceasa

Open access · diamondAbstract read
In one paragraph

Article in Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Mihaela PerţeaDepartment of Surgery, Department of Morphofunctional Sciences I, Grigore T. Popa University of Medicine and Pharmacy, Iaşi, Romania; sdlunca@yahoo.com, mihaela.mitrea77@yahoo.com.
Vladimir Poroch
Natalia Velenciuc
Mihaela Mitrea
Sorinel Luncă
Cristina Terinte
Alexandru Filip
Ovidiu Alexa
Bogdan Veliceasa
Grigore T. Popa University of Medicine and Pharmacy · ROInstitutul Regional de Oncologie · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeGlomus tumors account for 1-4% of benign hand tumors. In 65% of cases, it is located in the nail bed. Its rarity makes misdiagnosis problems relatively common. Symptomatology is characterized by the hallmark symptomatic triad. Imaging investigations may guide the diagnosis, but the diagnosis is made by pathological examination doubled by immunohistochemical (IHC) markers. PATIENTS, MATERIALS AND

methodsWe studied a group of seven female patients, aged 28 to 56 years. Clinical examination revealed the presence of the characteristic symptomatic triad. Ultrasound imaging tests were performed.

resultsAnatomopathological examination made a diagnosis of glomus tumor in all seven cases. IHC staining showed that tumor cells were positive for alpha-smooth muscle actin (α-SMA) and h-caldesmon in all seven cases and negative for cluster of differentiation 34 (CD34) in 72.14%. IHC stainings for p63, S100, cytokeratin (CK) AE1∕AE3 were negative in all cases. The clinical diagnosis completed by ultrasonography was histopathologically confirmed in all cases.

conclusionsAlthough the glomus tumor is a rare lesion, we need to be familiar with it because a diagnostic delay also implies a treatment delay which will lead to amplified suffering and even real disability due to the high-intensity pain in these cases.

Indexed as

Glomus TumorDelayed DiagnosisFemaleHandHumansNails

Identifiers

PMID34609426
PMCPMC8597357
OpenAlexW3204337072

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.