Evidence map›Paper›PMID 34609299›Full record

ArticleThe Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology2021

Recommendations for Hepatitis B Immunoglobulin and Antiviral Prophylaxis Against Hepatitis B Recurrence After Liver Transplantation.

Mesut Akarsu, Soner Onem, Ilker Turan, Gupse Adali, Meral Akdogan, Murat Akyildiz, Murat Aladag, Yasemin Balaban, Nilay Danis, Murat Dayangac and 10 more

Open access · greenAbstract read
In one paragraph

Article in The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 12 institutions in 1 country.

Mesut AkarsuDepartment of Gastroenterology, Dokuz Eylül University School of Medicine, İzmir, Turkey.
Soner OnemDepartment of Gastroenterology, Ege University School of Medicine, Izmir, Turkey.
Ilker TuranDepartment of Gastroenterology, Ege University School of Medicine, Izmir, Turkey.
Gupse AdaliDepartment of Gastroenterology, University of Health Sciences, Umraniye Training and Research Hospital, Istanbul, Turkey.
Meral AkdoganDepartment of Gastroenterology, University of Health Sciences, Ankara City Hospital, Ankara, Turkey.
Murat AkyildizDepartment of Gastroenterology, Koc University School of Medicine, Istanbul, Turkey.
Murat AladagDepartment of Gastroenterology, Turgut Özal University School of Medicine, Malatya, Turkey.
Yasemin BalabanDepartment of Gastroenterology, Hacettepe University School of Medicine, Ankara, Turkey.
Nilay DanisDepartment of Gastroenterology, Ege University School of Medicine, Izmir, Turkey.
Murat DayangacCenter for Organ Transplantation, Medipol University Hospital, Istanbul, Turkey.
Genco GencdalDepartment of Gastroenterology, Koc University School of Medicine, Istanbul, Turkey.
Hale GokcanDepartment of Gastroenterology, Ankara University School of Medicine, Ankara, Turkey.
Elif SertesenDepartment of Gastroenterology, Ankara University School of Medicine, Ankara, Turkey.
Merve GurakarDepartment of Gastroenterology, Ankara University School of Medicine, Ankara, Turkey.
Murat HarputluogluDepartment of Gastroenterology, Liver Transplantation Institute, İnönü University School of Medicine, Malatya, Turkey.
Gokhan KabacamDepartment of Gastroenterology, Güven Hospital, Ankara, Turkey.
Sedat KarademirDepartment of Gastroenterology, Güven Hospital, Ankara, Turkey.
Murat KiyiciDepartment of Gastroenterology, Uludag University School of Medicine, Bursa, Turkey.
Ramazan IdilmanDepartment of Gastroenterology, Ankara University School of Medicine, Ankara, Turkey.
Zeki KarasuDepartment of Gastroenterology, Ege University School of Medicine, Izmir, Turkey.
Ankara University · TREge University · TRGüven Hospital · TRKoç University · TRBursa Uludağ Üni̇versi̇tesi̇ · TRDokuz Eylül University · TRHacettepe University · TRInonu University · TRIstanbul Medipol University · TRSağlık Bilimleri Üniversitesi · TRTurgut Özal University · TRÜmraniye Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The combination of hepatitis B immunoglobulin and potent nucleos(t)ide analogs after liver transplantation is considered as the standard of care for prophylaxis against hepatitis B virus recurrence. However, the recommended doses, route of administration, and duration of HBIG administration remain unclear. Moreover, hepatitis B immunoglobulin-free prophylaxis with potent nucleos(t)ide analogs has shown promising disease outcomes in preventing hepatitis B virus recurrence. The current recommendations, produced by the Turkish Association for the Study of the Liver, Acute Liver Failure and Liver Transplantation Special Interest Group, suggest a reduced need for hepatitis B immunoglobulin administration with effective long-term suppression of hepatitis B virus replication using potent nucleos(t) ide analogs after liver transplantation.

Indexed as

Antiviral AgentsHepatitis BImmunoglobulinsLiver TransplantationHumansRecurrenceAntiviral Agentshepatitis B hyperimmune globulinImmunoglobulins

Identifiers

PMID34609299
PMCPMC8975456
OpenAlexW3199323896

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.