Evidence map›Paper›PMID 34609137›Full record

ArticleThe Journal of organic chemistry2021

"How Should I Think about Voltage? What Is Overpotential?": Establishing an Organic Chemistry Intuition for Electrochemistry.

Jordan E Nutting, James B Gerken, Alexios G Stamoulis, David L Bruns, Shannon S Stahl

Abstract read
In one paragraph

Article in The Journal of organic chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Deep reduction in electrosynthesis.Nature chemistry · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Selective Toluene Electrooxidation to Benzyl Alcohol.Journal of the American Chemical Society · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Site-Selective Electrochemical Arene C-H Amination.Journal of the American Chemical Society · 2024
    Article
  14. Article
  15. Optimizing the Synthetic Potential of OJournal of the American Chemical Society · 2023
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jordan E NuttingDepartment of Chemistry, University of Wisconsin─Madison, 1101 University Avenue, Madison, Wisconsin 53706-1322, United States.ORCID 0000-0003-4017-8834
James B GerkenDepartment of Chemistry, University of Wisconsin─Madison, 1101 University Avenue, Madison, Wisconsin 53706-1322, United States.
Alexios G StamoulisDepartment of Chemistry, University of Wisconsin─Madison, 1101 University Avenue, Madison, Wisconsin 53706-1322, United States.
David L BrunsDepartment of Chemistry, University of Wisconsin─Madison, 1101 University Avenue, Madison, Wisconsin 53706-1322, United States.ORCID 0000-0003-2455-502X
Shannon S StahlDepartment of Chemistry, University of Wisconsin─Madison, 1101 University Avenue, Madison, Wisconsin 53706-1322, United States.ORCID 0000-0002-9000-7665

Funding

Catalytic Redox Reactions for Pharmaceutical SynthesisR35GM134929 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Shannon S Stahl · 2020 to 2026
$4.3M
NIGMS NIH HHS R35 GM134929
6 · The paper itself

Abstract

Redox reactions are ubiquitous in organic synthesis and intrinsic to organic electrosynthesis. The language and concepts used to describe reactions in these domains are sufficiently different to create barriers that hinder broader adoption and understanding of electrochemical methods. To bridge these gaps, this Synopsis compares chemical and electrochemical redox reactions, including concepts of free energy, voltage, kinetic barriers, and overpotential. This discussion is intended to increase the accessibility of electrochemistry for organic chemists lacking formal training in this area.

Indexed as

Chemistry, OrganicIntuitionElectrochemical TechniquesElectrochemistryOxidation-Reduction

Identifiers

PMID34609137
PMCPMC8604791

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.