Evidence map›Paper›PMID 34609135›Full record

ArticleBiochemistry2021

NMR and EPR-DEER Structure of a Dimeric Guanylate Cyclase Activator Protein-5 from Zebrafish Photoreceptors.

Diana Cudia, Graham P Roseman, Tufa E Assafa, Manisha Kumari Shahu, Alexander Scholten, Sarah-Karina Menke-Sell, Hiroaki Yamada, Karl-W Koch, Glenn Milhauser, James B Ames

Open access · greenAbstract read
In one paragraph

Article in Biochemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Diana CudiaDepartment of Chemistry, University of California, Davis, California 95616, United States.
Graham P RosemanDepartment of Chemistry and Biochemistry, University of California, Santa Cruz, California 95064, United States.
Tufa E AssafaDepartment of Chemistry and Biochemistry, University of California, Santa Cruz, California 95064, United States.
Manisha Kumari ShahuDivision of Biochemistry, Department of Neuroscience, University of Oldenburg, 26129 Oldenburg, Germany.
Alexander ScholtenDivision of Biochemistry, Department of Neuroscience, University of Oldenburg, 26129 Oldenburg, Germany.
Sarah-Karina Menke-SellDivision of Biochemistry, Department of Neuroscience, University of Oldenburg, 26129 Oldenburg, Germany.
Hiroaki YamadaDepartment of Chemistry, University of California, Davis, California 95616, United States.
Karl-W KochDivision of Biochemistry, Department of Neuroscience, University of Oldenburg, 26129 Oldenburg, Germany.ORCID 0000-0003-1501-0044
Glenn MilhauserDepartment of Chemistry and Biochemistry, University of California, Santa Cruz, California 95064, United States.ORCID 0000-0003-2442-7220
James B AmesDepartment of Chemistry, University of California, Davis, California 95616, United States.ORCID 0000-0003-0934-2595
Carl von Ossietzky Universität Oldenburg · DEUniversity of California, Davis · USUniversity of California, Santa Cruz · US

Funding

MEMBRANE TARGETING CALCIUM SENSORS IN VISIONR01EY012347 · NEI · UNIVERSITY OF MD BIOTECHNOLOGY INSTITUTE · PI AMES, JAMES B · 1999 to 2023
$6.9M
Supplement Request for Emergency Replacement of EPR Amplifier and Acquisition of a Low Volume Resonator for Membrane ProteinsR35GM131781 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI GLENN L MILLHAUSER · 2019 to 2026
$3.6M
Upgrade of a Pulsed Electron Paramagnetic Resonance SpectrometerS10OD024980 · OD · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI MILLHAUSER, GLENN L · 2018 to 2018
$1.5M
NEI NIH HHS R01 EY012347NIGMS NIH HHS R35 GM131781NIH HHS S10 OD024980
6 · The paper itself

Abstract

Retinal guanylate cyclases (RetGCs) are regulated by a family of guanylate cyclase-activating proteins (called GCAP1-7). GCAPs form dimers that bind to Ca

Indexed as

Amino Acid SequenceAnimalsCysteineElectron Spin Resonance SpectroscopyGuanylate Cyclase-Activating ProteinsMagnesiumMolecular Docking SimulationMutationNuclear Magnetic Resonance, BiomolecularProtein BindingProtein MultimerizationProtein Structure, QuaternaryZebrafishZebrafish ProteinsCysteineGuanylate Cyclase-Activating Proteinsguca1e protein, zebrafishMagnesiumZebrafish Proteins

Identifiers

PMID34609135
PMCPMC8944188
OpenAlexW3203675618

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.