Evidence map›Paper›PMID 34609065›Full record

ArticleJournal of cachexia, sarcopenia and muscle2021

Diagnosis of sarcopenia by evaluating skeletal muscle mass by adjusted bioimpedance analysis validated with dual-energy X-ray absorptiometry.

Keith Yu-Kin Cheng, Simon Kwoon-Ho Chow, Vivian Wing-Yin Hung, Carissa Hing-Wai Wong, Ronald Man-Yeung Wong, Charlotte Sau-Lan Tsang, Timothy Kwok, Wing-Hoi Cheung

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Journal of cachexia, sarcopenia and muscle, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 107 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed, 4 pooled it
9.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05869487 narecruitingnot on this mapstarted 2023, after this paper: background citation

Evaluation of a Diagnostic Method: Calf Circumference Versus X-ray Absorptiometry in the Diagnosis of Sarcopenia in Elderly Hospitalized Participants

TypeinterventionalSponsorCentre Hospitalier Régional d'OrléansRan2023 to 2027Enrolled298ConditionsSarcopeniaArmsDual-energy X-ray absorptiometry
NCT05991778 completednot on this map

Bioelectrical Impedance Vector Analysis (BIVA) in Monitoring Hyperhydration and Polyneuromyopathy in Critically Ill Patients

TypeobservationalSponsorUniversity Hospital OstravaRan2021 to 2022Enrolled61ConditionsRespiratory Distress Syndrome, Acute, Respiratory Insufficiency, Lung Ventilator, HyperhydrationArmsBioelectrical impedance vector analysis (BIVA), Blood and urine analysis, cumulative water balance
3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 4 syntheses or guidelines pooled it, 139 citations in OpenAlex.

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  19. Muscle Ultrasound Echo Intensity Detects Insulin Resistance Before Changes in HbAJournal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026
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  20. [Correlational research on body fat rate and skeletal muscle rate with depression in the population of assisted reproduction].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2026
    Article

47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Keith Yu-Kin ChengBone Quality and Health Centre, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, Hong Kong.
Simon Kwoon-Ho ChowBone Quality and Health Centre, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, Hong Kong.ORCID 0000-0003-1742-980X
Vivian Wing-Yin HungBone Quality and Health Centre, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, Hong Kong.
Carissa Hing-Wai WongBone Quality and Health Centre, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, Hong Kong.
Ronald Man-Yeung WongBone Quality and Health Centre, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, Hong Kong.
Charlotte Sau-Lan TsangBone Quality and Health Centre, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, Hong Kong.
Timothy KwokBone Quality and Health Centre, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, Hong Kong.
Wing-Hoi CheungBone Quality and Health Centre, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, Hong Kong.
Chinese University of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to adjust and cross-validate skeletal muscle mass measurements between bioimpedance analysis (BIA) and dual-energy X-ray absorptiometry (DXA) for the screening of sarcopenia in the community and to estimate the prevalence of sarcopenia in Hong Kong.

methodsScreening of sarcopenia was provided to community-dwelling older adults. Appendicular skeletal muscle mass (ASM) was evaluated by BIA (InBody 120 or 720) and/or DXA. Handgrip strength and/or gait speed were assessed. Diagnosis of sarcopenia was based on the 2019 revised Asian Working Group for Sarcopenia cut-offs. Agreement analysis was performed to cross-validate ASM measurements by BIA and DXA. Multiple regression was used to explore contribution of measured parameters in predicting DXA ASM from BIA.

resultsA total of 1587 participants (age = 72 ± 12 years) were recruited; 1065 participants were screened by BIA (InBody 120) with 18 followed up by DXA, while the remaining 522 participants were assessed by the BIA (InBody 720) and DXA. The appendicular skeletal muscle mass index (ASMI) evaluated by BIA showed a mean difference of 2.89 ± 0.38 kg/m

conclusionsBioimpedance analysis was found to overestimate skeletal muscle mass compared with DXA. With adjustment equations, BIA can be used as a quick and reliable tool for screening sarcopenia in community and clinical settings with limited access to better options.

Indexed as

SarcopeniaAbsorptiometry, PhotonAgedAged, 80 and overBody CompositionElectric ImpedanceHand StrengthHumansMiddle AgedMuscle, SkeletalBioimpedance analysis (BIA)DiagnosisDual-energy X-ray absorptiometry (DXA)SarcopeniaSkeletal muscle mass

Identifiers

PMID34609065
PMCPMC8718029
OpenAlexW3202032823

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.