Observational studyInternational wound journal2022
Diagnosis and treatment of the invasive extension of bacteria (cellulitis) from chronic wounds utilising point-of-care fluorescence imaging.
Observational study in International wound journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Artificial Intelligence Methods for Diagnostic and Decision-Making Assistance in Chronic Wounds: A Systematic Review.Journal of medical systems · 2025Pooled it
- Development of Antiseptic and Epidermal Growth Factor Co-Loaded Thermoresponsive Composite Hydrogel for Wound Healing: Fabrication, Characterization, and In Vitro Functional Assessment.Gels (Basel, Switzerland) · 2026Article
- Use of Polylactic Acid Dermal Matrix for the Management of Wounds with Exposed Avascular Structures.Journal of clinical medicine · 2025Article
- Clinical and Economic Evidence Supporting the Value of Fluorescence Imaging of Bacteria in Wound Care.Journal of market access & health policy · 2025Review
- Lights, fluorescence, action-Influencing wound treatment plans including debridement of bacteria and biofilms.International wound journal · 2023Article
- Point-of-care fluorescence imaging reveals extent of bacterial load in diabetic foot ulcers.International wound journal · 2023Article
- Uncovering the high prevalence of bacterial burden in surgical site wounds with point-of-care fluorescence imaging.International wound journal · 2022Article
- Diagnosis and treatment of the invasive extension of bacteria (cellulitis) from chronic wounds utilising point-of-care fluorescence imaging.International wound journal · 2022Observational
- Use of fluorescence imaging to optimize location of tissue sampling in hard-to-heal wounds.Frontiers in cellular and infection microbiology · 2022Article
- New Medical Device and Therapeutic Approvals in Otolaryngology: State of the Art Review of 2022.OTO openArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Early diagnosis of wound-related cellulitis is challenging as many classical signs and symptoms of infection (erythema, pain, tenderness, or fever) may be absent. In addition, other conditions (ie, chronic stasis dermatitis) may present with similar clinical findings. Point-of-care fluorescence imaging detects elevated bacterial burden in and around wounds with high sensitivity. This prospective observational study examined the impact of incorporating fluorescence imaging into standard care for diagnosis and management of wound-related cellulitis. Two hundred thirty-six patients visiting an outpatient wound care centre between January 2020 and April 2021 were included in this study. Patients underwent routine fluorescence scans for bacteria (range: 1-48 scans/patient). Wound-related cellulitis was diagnosed in 6.4% (15/236) of patients. In these patients, fluorescence scans showed an irregular pattern of red (bacterial) fluorescence extending beyond the wound bed and periwound that could not be removed through cleansing or debridement, indicating the invasive extension of bacteria (wound-related cellulitis). Point-of-care identification facilitated rapid initiation of treatments (source control and antibiotics, when warranted) that resolved the fluorescence. No patients had worsening of cellulitis requiring intravenous antibiotics and/or hospitalisation. These findings demonstrate the utility of point-of-care fluorescence imaging for efficient detection and proactive, targeted management of wound-related cellulitis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.