Evidence map›Paper›PMID 34608761›Full record

ArticlePediatric obesity2022

Central obesity in school-aged children increases the likelihood of developing paediatric autoimmune diseases.

Laura Räisänen, Sohvi Lommi, Elina Engberg, Kaija-Leena Kolho, Heli Viljakainen

Open access · hybridAbstract read
In one paragraph

Article in Pediatric obesity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Inflammatory Bowel Disease in Children and Young People Living With Overweight or Obesity: A Critical Narrative Review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Laura RäisänenFin-HIT Research Group, Folkhälsan Research Center, Helsinki, Finland.ORCID 0000-0002-4892-5710
Sohvi LommiFin-HIT Research Group, Folkhälsan Research Center, Helsinki, Finland.ORCID 0000-0002-4393-5725
Elina EngbergFin-HIT Research Group, Folkhälsan Research Center, Helsinki, Finland.ORCID 0000-0002-8713-5607
Kaija-Leena KolhoFaculty of Medicine and Health Technology (MET), Tampere University, Tampere, Finland.ORCID 0000-0001-9170-8415
Heli ViljakainenFin-HIT Research Group, Folkhälsan Research Center, Helsinki, Finland.ORCID 0000-0002-7486-3437
University of Helsinki · FITampere University of Applied Sciences · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidences of both paediatric obesity and autoimmune diseases have been increasing, but their relationship with one another is unclear.

objectiveTo determine whether obesity or particular dietary patterns in school-aged children are potential risk factors for autoimmune diseases during adolescence.

methodsThis matched case-control study included 525 children, followed up from a median age of 11.3 to 16.7 years. Of them, 105 children received primary autoimmune diagnoses (diabetes, thyroiditis, arthritis, or inflammatory bowel diseases) after baseline and generated the case group. Four children with matching age, sex, and residential area generated the control group of 420 children. At baseline, age- and sex-specific body mass index categories were acquired and waist-to-height ratio (WHTR) was calculated. Central obesity was present when WHTR ≥0.5. Dietary patterns were analysed using a food frequency questionnaire (FFQ).

resultsSchool-aged children with central obesity were 2.11 (OR, 95% CI 1.11-3.98) times more likely to develop autoimmune diseases before age of 19 years than those without central obesity. Being overweight was not related to the onset of these diseases (OR 1.60, 95% CI 0.89-2.87, nor were dietary patterns.

conclusionCentral obesity in school-aged children was related to the development of autoimmune diseases, while being overweight and dietary patterns were not.

Indexed as

Autoimmune DiseasesPediatric ObesityAdolescentAdultBody Mass IndexCase-Control StudiesChildFemaleHumansMaleObesity, AbdominalOverweightYoung Adultautoimmune thyroiditis (AIT)dietary patternseating habitsinflammatory bowel diseases (IBD)juvenile idiopathic arthritis (JIA)type 1 diabetes (DM)

Identifiers

PMID34608761
PMCPMC9285017
OpenAlexW3203303273

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.