Evidence map›Paper›PMID 34608616›Full record

ArticleNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics2021

Neuroprotective Roles of the Adenosine A

Eda Bozdemir, Fabio A Vigil, Sang H Chun, Liliana Espinoza, Vladislav Bugay, Sarah M Khoury, Deborah M Holstein, Aiola Stoja, Damian Lozano, Ceyda Tunca and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
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  4. Review
  5. Article
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  7. Article
  8. Review
  9. Extrahelical Binding Site for a 1Molecular pharmacology · 2024
    Article
  10. Review
  11. Species dependence of APurinergic signalling · 2023
    Review
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Eda Bozdemir *Department of Cell Systems and Anatomy, UT Health San Antonio, 8403 Floyd Curl Drive, San Antonio, TX, 78229-3904, USA.
Fabio A Vigil *Department of Cellular and Integrative Physiology, UT Health San Antonio, 8403 Floyd Curl Drive, San Antonio, TX, 78229-3904, USA.
Sang H ChunDepartment of Cell Systems and Anatomy, UT Health San Antonio, 8403 Floyd Curl Drive, San Antonio, TX, 78229-3904, USA.
Liliana EspinozaDepartment of Cellular and Integrative Physiology, UT Health San Antonio, 8403 Floyd Curl Drive, San Antonio, TX, 78229-3904, USA.
Vladislav BugayDepartment of Cellular and Integrative Physiology, UT Health San Antonio, 8403 Floyd Curl Drive, San Antonio, TX, 78229-3904, USA.
Sarah M KhouryDepartment of Cell Systems and Anatomy, UT Health San Antonio, 8403 Floyd Curl Drive, San Antonio, TX, 78229-3904, USA.
Deborah M HolsteinDepartment of Cell Systems and Anatomy, UT Health San Antonio, 8403 Floyd Curl Drive, San Antonio, TX, 78229-3904, USA.
Aiola StojaDepartment of Cellular and Integrative Physiology, UT Health San Antonio, 8403 Floyd Curl Drive, San Antonio, TX, 78229-3904, USA.
Damian LozanoDepartment of Cell Systems and Anatomy, UT Health San Antonio, 8403 Floyd Curl Drive, San Antonio, TX, 78229-3904, USA.
Ceyda TuncaDepartment of Cell Systems and Anatomy, UT Health San Antonio, 8403 Floyd Curl Drive, San Antonio, TX, 78229-3904, USA.
Shane M SpragueDepartment of Neurosurgery, UT Health San Antonio, 7703 Floyd Curl Drive, San Antonio, TX, 78229-3904, USA.
Jose E CavazosDepartment of Neurology, UT Health San Antonio, 7703 Floyd Curl Drive, San Antonio, TX, 78229-3904, USA.
Robert BrennerDepartment of Cellular and Integrative Physiology, UT Health San Antonio, 8403 Floyd Curl Drive, San Antonio, TX, 78229-3904, USA.
Theodore E ListonAstrocyte Pharmaceuticals Inc, 245 First Street, Suite 1800, Cambridge, MA, 02142, USA.
Mark S ShapiroDepartment of Cellular and Integrative Physiology, UT Health San Antonio, 8403 Floyd Curl Drive, San Antonio, TX, 78229-3904, USA.
James D LechleiterDepartment of Cell Systems and Anatomy, UT Health San Antonio, 8403 Floyd Curl Drive, San Antonio, TX, 78229-3904, USA. lechleiter@uthscsa.edu.ORCID http://orcid.org/0000-0001-9000-0722
The University of Texas Health Science Center at San Antonio · US

Funding

TISSUE CULTURE---COREP30CA054174 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Robin Jean Leach · 1991 to 2026
$59.1M
Targeting specific interactions between A-kinase Anchoring Proteins (AKAPs) and ion channels with cell-permeant peptides as a novel mode of therapeutic intervention against pain disordersR01NS094461 · NINDS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI SHAPIRO, MARK S · 2015 to 2019
$2.0M
Mechanism and functional role of AKAP79/150 in M current control and excitabilityR01NS065138 · NINDS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI SHAPIRO, MARK S · 2009 to 2010
$788k
NCI NIH HHS P30 CA054174NINDS NIH HHS R01 NS065138NINDS NIH HHS R01 NS094461
6 · The paper itself

Abstract

Traumatic brain injury (TBI) remains one of the greatest public health concerns with increasing morbidity and mortality rates worldwide. Our group reported that stimulation of astrocyte mitochondrial metabolism by P2Y

Indexed as

Brain Injuries, TraumaticNeuroprotective AgentsAdenosineAnimalsAstrocytesDisease Models, AnimalFemaleGliosisMaleMiceMice, Inbred C57BLNeuroprotectionAdenosineNeuroprotective AgentsADORA3AstrocytesATPConcussion treatmentMitochondrial metabolism

Identifiers

PMID34608616
PMCPMC8804149
OpenAlexW3172864059

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.