Evidence map›Paper›PMID 34608233›Full record

ArticleScientific reports2021

The MRI posterior drawer test to assess posterior cruciate ligament functionality and knee joint laxity.

Lena Marie Wollschläger, Karl Ludger Radke, Justus Schock, Niklas Kotowski, David Latz, Dominika Kanschik, Timm Joachim Filler, Svenja Caspers, Gerald Antoch, Joachim Windolf and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Lena Marie WollschlägerDepartment of Diagnostic and Interventional Radiology, Medical Faculty, University Dusseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany.
Karl Ludger RadkeDepartment of Diagnostic and Interventional Radiology, Medical Faculty, University Dusseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany.
Justus SchockDepartment of Diagnostic and Interventional Radiology, Medical Faculty, University Dusseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany.
Niklas KotowskiDepartment of Diagnostic and Interventional Radiology, Aachen University Hospital, Aachen, Germany.
David LatzDepartment of Orthopaedics and Trauma Surgery, Medical Faculty, University Dusseldorf, 40225, Düsseldorf, Germany.
Dominika KanschikDepartment of Diagnostic and Interventional Radiology, Medical Faculty, University Dusseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany.
Timm Joachim FillerInstitute of Anatomy I, Heinrich-Heine-University, 40225, Düsseldorf, Germany.
Svenja CaspersInstitute of Anatomy I, Heinrich-Heine-University, 40225, Düsseldorf, Germany.
Gerald AntochDepartment of Diagnostic and Interventional Radiology, Medical Faculty, University Dusseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany.
Joachim WindolfDepartment of Orthopaedics and Trauma Surgery, Medical Faculty, University Dusseldorf, 40225, Düsseldorf, Germany.
Daniel Benjamin AbrarDepartment of Diagnostic and Interventional Radiology, Medical Faculty, University Dusseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany.
Sven NebelungDepartment of Diagnostic and Interventional Radiology, Medical Faculty, University Dusseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany. sven.nebelung@med.uni-duesseldorf.de.
Heinrich Heine University Düsseldorf · DEUniversitätsklinikum Aachen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical Magnetic Resonance Imaging (MRI) of joints is limited to mere morphologic evaluation and fails to directly visualize joint or ligament function. In this controlled laboratory study, we show that knee joint functionality may be quantified in situ and as a function of graded posterior cruciate ligament (PCL)-deficiency by combining MRI and standardized loading. 11 human knee joints underwent MRI under standardized posterior loading in the unloaded and loaded (147 N) configurations and in the intact, partially, and completely PCL-injured conditions. For each specimen, configuration, and condition, 3D joint models were implemented to analyse joint kinematics based on 3D Euclidean vectors and their projections on the Cartesian planes. Manual 2D measurements served as reference. With increasing PCL deficiency, vector projections increased significantly in the anteroposterior dimension under loading and manual measurements demonstrated similar patterns of change. Consequently, if combined with advanced image post-processing, stress MRI is a powerful diagnostic adjunct to evaluate ligament functionality and joint laxity in multiple dimensions and may have a role in differentiating PCL injury patterns, therapeutic decision-making, and treatment monitoring.

Indexed as

Magnetic Resonance ImagingAgedAged, 80 and overFemaleHumansImage Processing, Computer-AssistedImaging, Three-DimensionalJoint InstabilityKnee InjuriesKnee JointMaleMiddle AgedPosterior Cruciate Ligament

Identifiers

PMID34608233
PMCPMC8490383
OpenAlexW3202825035

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.