Evidence map›Paper›PMID 34607919›Full record

ArticleLife science alliance2021

Loss of

Matúš Vojtek, Ian Chambers

Open access · goldAbstract read
In one paragraph

Article in Life science alliance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Matúš VojtekCentre for Regenerative Medicine, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, Scotland.ORCID 0000-0001-6646-1238
Ian ChambersCentre for Regenerative Medicine, Institute for Regeneration and Repair, University of Edinburgh, Edinburgh, Scotland ichambers@ed.ac.uk.ORCID 0000-0003-2605-1597
MRC Centre for Regenerative Medicine · GB

Funding

Medical Research Council MR/T003162/1
6 · The paper itself

Abstract

Retroelement silencing factor 1 (RESF1) interacts with the key regulators of mouse embryonic stem cells (ESCs) OCT4 and NANOG, and its absence results in sterility of mice. However, the function of RESF1 in ESCs and germline specification is poorly understood. In this study, we used

Indexed as

AnimalsCell DifferentiationCell LineCell Self RenewalCloning, MolecularGene Knockout TechniquesGerm CellsLeukemia Inhibitory FactorMiceMouse Embryonic Stem CellsNanog Homeobox ProteinPlasmidsReceptors, EstrogenRepressor ProteinsSignal TransductionTransfectionEsrrb protein, mouseLeukemia Inhibitory FactorLif protein, mouseNanog Homeobox ProteinNanog protein, mouseReceptors, EstrogenRepressor ProteinsResf1 protein, mouse

Identifiers

PMID34607919
PMCPMC8500223
OpenAlexW3202100416

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.