ArticleBMJ open2021
Demographic, lifestyle and comorbid risk factors for all-cause mortality in a Danish cohort of middle-aged adults with incident asthma.
Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.
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Who cites it
5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 7 citations in OpenAlex.
- Physical Activity, Air Pollution, and Mortality: A Systematic Review and Meta-analysis.Sports medicine - open · 2025Pooled it
- Asthma and the risk of cardiovascular diseases and mortality: a meta-analysis of cohort studies.Therapeutic advances in respiratory diseasePooled it
- Association of oxidative balance scores with cardiovascular and all cause mortality in patients with asthma.Scientific reports · 2025Article
- Association of Life's Essential 8 with all-cause mortality in asthma patients: evidence from NHANES 2005-2018.Frontiers in nutrition · 2025Article
- Is overreliance on short-acting βERJ open research · 2022Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe aimed to identify factors associated with all-cause mortality in adults with incident asthma. DESIGN AND
settingCross-sectional cohort study, in the metropolitan areas of Copenhagen and Aarhus, Denmark.
participantsAdults aged 50-64 years enrolled in the Danish Diet, Cancer, and Health cohort were followed up from baseline (1993-1997) in the National Patients Registry for first-time admissions for asthma and vital status. We defined incident asthma as at least one first-time hospital admission with asthma as the primary registered diagnosis between baseline and end of follow-up (2013) in participants without previously known asthma. Among the cohort comprising 57 053 individuals, we identified 785 adults (aged 50-64) with incident asthma, of whom 76 died during follow-up. PRIMARY AND SECONDARY OUTCOME MEASURES: Baseline reported socioeconomic and lifestyle traits, and comorbidities associated with all-cause mortality.
resultsSelf-reported leisure-time physical activity was associated with a substantial reduction in risk with an HR of 0.53 (95% CI 0.33 to 0.85). Being male, single and having a diagnosis of hypertension or diabetes were associated with an increased risk of all-cause mortality with an HR of 1.83 (95% CI 1.14 to 2.38), 2.16 (95% CI 2.06 to 4.40), 2.47 (95% CI 1.54 to 3.95) and of 2.42 (95% CI 0.96 to 6.11), respectively.
conclusionsThis long-term study of adults with hospital contacts for incident asthma revealed that self-reported leisure-time physical activity is associated with an approximately 50% reduction in all-cause mortality. In contrast, both hypertension and diabetes were associated with a higher risk of mortality.
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