Evidence map›Paper›PMID 34607795›Full record

ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2021

Faecal calprotectin testing in UK general practice: a retrospective cohort study using The Health Improvement Network database.

Karoline Freeman, Ronan Ryan, Nicholas Parsons, Sian Taylor-Phillips, Brian H Willis, Aileen Clarke

Open access · hybridAbstract read
In one paragraph

Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Reply to comments on pregnancy and inflammatory bowel diseases.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Article
  2. Evaluating the role of faecal calprotectin in older adults: a retrospective observational study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2026
    Observational
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Karoline FreemanWarwick Medical School, University of Warwick, Coventry.
Ronan RyanInstitute of Applied Health Research, University of Birmingham, Birmingham.
Nicholas ParsonsWarwick Medical School, University of Warwick, Coventry.
Sian Taylor-PhillipsWarwick Medical School, University of Warwick, Coventry.
Brian H WillisInstitute of Applied Health Research, University of Birmingham, Birmingham.
Aileen ClarkeWarwick Medical School, University of Warwick, Coventry.
University of Warwick · GBUniversity of Birmingham · GB

Funding

Medical Research Council MR/N007999/1
6 · The paper itself

Abstract

backgroundFaecal calprotectin (FC) testing to detect inflammatory bowel disease (IBD) was recommended for use in UK general practice in 2013. The actual use of FC testing following the national recommendations is unknown.

aimTo characterise the use of FC testing for IBD in UK general practice. DESIGN AND

settingA retrospective cohort study of routine electronic patient records from The Health Improvement Network database from UK general practice.

methodThe study included 6 965 853 adult patients (aged ≥18 years), between 2006 and 2016. FC test uptake, the patients tested, and patient management following testing were characterised.

resultsA total of 17 027 patients had 19 840 FC tests recorded. The mean age of tested patients was 44.2 years. The first FC tests were documented in 2009. FC test use was still increasing in 2016. By 2016, 66.8% (

conclusionUptake of FC testing in clinical practice has been slow and inconsistent. The indication of non-compliance with national recommendations may suggest that these recommendations lack applicability to the general practice context.

Indexed as

General PracticeInflammatory Bowel DiseasesAdolescentAdultBiomarkersFecesHumansLeukocyte L1 Antigen ComplexRetrospective StudiesUnited KingdomBiomarkersLeukocyte L1 Antigen Complexdiagnostic testsgeneral practiceinflammatory bowel diseasespractice guidelines as topic

Identifiers

PMID34607795
PMCPMC8510694
OpenAlexW3202496944

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.