Evidence map›Paper›PMID 34607722›Full record

SynthesisEuropean neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology2022

Outcomes associated with different vaccines in individuals with bipolar disorder and impact on the current COVID-19 pandemic- a systematic review.

Eva Z Reininghaus, Mirko Manchia, Nina Dalkner, Nina Bonkat, Alessio Squassina, Isabel Hodl, Eduard Vieta, Andreas Reif, Tomas Hajek, Mikael Landén and 23 more

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Psychotropic drug repurposing for COVID-19: A Systematic Review and Meta-Analysis.European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology · 2023
    Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors at 20 institutions in 13 countries.

Eva Z ReininghausMedical University Graz, Department of Psychiatry & Psychotherapeutic Medicine.
Mirko ManchiaUnit of Psychiatry, Department of Medical Sciences and Public Health, University of Cagliari,Cagliari, Italy; Unit of Clinical Psychiatry, University Hospital Agency of Cagliari, Cagliari, Italy; Department of Pharmacology, Dalhousie University, Halifax, NS, Canada.
Nina DalknerMedical University Graz, Department of Psychiatry & Psychotherapeutic Medicine.
Nina BonkatMedical University Graz, Department of Psychiatry & Psychotherapeutic Medicine.
Alessio SquassinaLaboratory of Pharmacogenomics, Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy.
Isabel HodlMedical University Graz, Klinische Abteilung für Rheumatologie und Immunologie.
Eduard VietaInstitute of Neuroscience, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Catalonia, Spain.
Andreas ReifDepartment of Psychiatry, Psychosomatic Medicine and Psychotherapy; University Hospital Frankfurt, Frankfurt am Main, Germany.
Tomas HajekDalhousie University, Department of Psychiatry, Canada National Institute of Mental Health Klecany, Czech Republic; National Institute of Mental Health Klecany, Czech Republic.
Mikael LandénDepartment of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Christoph U CorrellCharité Universitätsmedizin Berlin, Department of Child and Adolescent Psychiatry, Berlin, Germany; Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Department of Psychiatry and Molecular Medicine, Hempstead, NY, USA; The Zucker Hillside Hospital, Department of Psychiatry, Northwell Health, Glen Oaks, NY, USA.
Jan ScottInstitute of Neuroscience, Newcastle University, Newcastle, UK.
Bruno EtainUniversite de Paris - INSERM UMRS 1144 - DMU Neurosciences, GHU Lariboisière Fernand Widal, Departement de Psychiatrie, APHP - Paris - France.
Marcella RietschelDepartment of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, University Heidelberg, Medical Faculty Mannheim, Mannheim, Germany.
Veerle BerginkDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, USA; Department of Psychiatry, Erasmus Medical Center, Rotterdam, the Netherlands.
Monica Martinez-CengotitabengoaOsakidetza, Basque Health Service, Health Service, BioAraba Research Institute, University of the Basque Country, Vitoria, Spain; The Psychology Clinic of East Anglia, Norwich, England.
Lars Vedel KessingCopenhagen Affective Disorder research Center (CADIC), Psychiatric Center Copenhagen, Copenhagen Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Andrea FagioliniUniversita di Siena, Molecular Medicine.
Michael BauerDepartment of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital Dresden, Technische Universität Dresden, Dresden, Germany.
Guy GoodwinDepartment of Psychiatry, University of Oxford, Oxford, United Kingdom.
Ana Gonzalez-PintoBIOARABA, Department of Neuroscience. UPV/EHU, CIBERSAM, Vitoria, Spain.
Ralph W KupkaDept. of Psychiatry, Amsterdam University Medical Centers, Vrije Universiteit, Amsterdam, Netherlands.
Thomas G SchulzeLMU University Hospital, Institute of Psychiatric Phenomics and Genomics (IPPG), Ludwig-Maximilians-University of Munich,Germany.
Trine V LagerbergNORMENT Centre, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Ayşegül YildizDokuz Eylul University Izmir, Turkey Department of Psychiatry.
Chantal HenryDepartement of Psychiatry, Service Hospitalo-Universitaire, GHU Paris Psychiatrie & Neurosciences, Paris, France, Université de Paris, Paris, France.
Gunnar MorkenSt Olav University Hospital and Norwegian University of Science and Technology - NTNU, Faculty of Medicine and Health Sciences.
Phillip RitterDepartment of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital Dresden, Technische Universität Dresden, Dresden, Germany.
René Ernst NieslenDepartment of Psychiatry, Aalborg University Hospital, Aalborg, Denmark; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.
Rasmus W LichtDepartment of Psychiatry, Aalborg University Hospital, Aalborg, Denmark; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.
Andreas BechdolfDepartment for Psychiatry, Psychotherapy and Psychosomatic, Vivantes Hospital am Urban and Friedrichshain; Charité Universitätsmedizin, Berlin, Germany.
Ole A AndreassenNORMENT Centre, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway; NORMENT Centre, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Frederike Tabea FellendorfMedical University Graz, Department of Psychiatry & Psychotherapeutic Medicine.
Medical University of Graz · ATAalborg University · DKUniversity Hospital Carl Gustav Carus · DEUniversity Hospital Frankfurt · DECentro de Investigación Biomédica en Red de Salud Mental · ESCharité - Universitätsmedizin Berlin · DEDalhousie University · CAErasmus MC · NLHeidelberg University · DEInserm · FRKarolinska Institutet · SELudwig-Maximilians-Universität München · DENational Institute of Mental Health · CZNewcastle University · GBNorwegian University of Science and Technology · NOOsakidetza · ESOslo University Hospital · NOUniversité Paris Cité · FRUniversity of Cagliari · ITUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bipolar disorder (BD) might be associated with higher infection rates of coronavirus disease (COVID-19) which in turn could result in worsening the clinical course and outcome. This may be due to a high prevalence of somatic comorbidities and an increased risk of delays in and poorer treatment of somatic disease in patients with severe mental illness in general. Vaccination is the most important public health intervention to tackle the ongoing pandemic. We undertook a systematic review regarding the data on vaccinations in individuals with BD. Proportion of prevalence rates, efficacy and specific side effects of vaccinations and in individuals with BD were searched. Results show that only five studies have investigated vaccinations in individuals with BD, which substantially limits the interpretation of overall findings. Studies on antibody production after vaccinations in BD are very limited and results are inconsistent. Also, the evidence-based science on side effects of vaccinations in individuals with BD so far is poor.

Indexed as

Bipolar DisorderCOVID-19VaccinesCommunicable Disease ControlCommunicable DiseasesHumansPandemicsSARS-CoV-2VaccinesBipolar disorderCOVID-19Infectious diseasesSystematic reviewVaccination

Identifiers

PMID34607722
PMCPMC8429356
OpenAlexW3200588572

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.