Evidence map›Paper›PMID 34607568›Full record

ArticleBMC bioinformatics2021

SicknessMiner: a deep-learning-driven text-mining tool to abridge disease-disease associations.

Nícia Rosário-Ferreira, Victor Guimarães, Vítor S Costa, Irina S Moreira

Abstract read
In one paragraph

Article in BMC bioinformatics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Scaling Biomedical Text-Mining: Transformers, GenAI, and Drug Discovery.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  2. Article
  3. Exploring novel disease-disease associations based on multi-view fusion network.Computational and structural biotechnology journal · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nícia Rosário-Ferreira *CQC - Coimbra Chemistry Center, Chemistry Department, Faculty of Science and Technology, University of Coimbra, 3004-535, Coimbra, Portugal. nicia.ferreira@student.uc.pt.
Victor Guimarães *Department of Sciences, University of Porto, Porto, Portugal.
Vítor S CostaDepartment of Sciences, University of Porto, Porto, Portugal.
Irina S MoreiraDepartment of Life Sciences, University of Coimbra, Calçada Martim de Freitas, 3000-456, Coimbra, Portugal. irina.moreira@cnc.uc.pt.

Funding

Fundação para a Ciência e a Tecnologia POCI-01-0145-FEDER-031356
6 · The paper itself

Abstract

backgroundBlood cancers (BCs) are responsible for over 720 K yearly deaths worldwide. Their prevalence and mortality-rate uphold the relevance of research related to BCs. Despite the availability of different resources establishing Disease-Disease Associations (DDAs), the knowledge is scattered and not accessible in a straightforward way to the scientific community. Here, we propose SicknessMiner, a biomedical Text-Mining (TM) approach towards the centralization of DDAs. Our methodology encompasses Named Entity Recognition (NER) and Named Entity Normalization (NEN) steps, and the DDAs retrieved were compared to the DisGeNET resource for qualitative and quantitative comparison.

resultsWe obtained the DDAs via co-mention using our SicknessMiner or gene- or variant-disease similarity on DisGeNET. SicknessMiner was able to retrieve around 92% of the DisGeNET results and nearly 15% of the SicknessMiner results were specific to our pipeline.

conclusionsSicknessMiner is a valuable tool to extract disease-disease relationship from RAW input corpus.

Indexed as

Deep LearningData MiningKnowledgeBiomedical text-miningBlood cancersDeep learningDisease-disease associationsNatural language processing

Identifiers

PMID34607568
PMCPMC8491382

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.