Evidence map›Paper›PMID 34607467›Full record

ArticlemBio2021

Para-Aminobenzoic Acid, Calcium, and c-di-GMP Induce Formation of Cohesive, Syp-Polysaccharide-Dependent Biofilms in Vibrio fischeri.

Courtney N Dial, Lauren Speare, Garrett C Sharpe, Scott M Gifford, Alecia N Septer, Karen L Visick

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 27 citations in OpenAlex.

  1. Tyrosine phosphorylation coupling of one-carbon metabolism and virulence in an endogenous pathogen.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Article
  3. A single point mutation is sufficient to driveJournal of bacteriology · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. One-carbon metabolism and microbial pathogenicity.Molecular oral microbiology · 2024
    Review
  8. Lighting the way: how theJournal of bacteriology · 2024
    Review
  9. Journal of bacteriology · 2024
    Review
  10. Article
  11. Regulatory mechanisms and applications ofFrontiers in microbiology · 2024
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. The type-VI secretion system of the beneficial symbiontMicrobiology (Reading, England) · 2023
    Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Courtney N DialDepartment of Microbiology and Immunology, Loyola University Chicago, Maywood, Illinois, USA.
Lauren SpeareDepartment of Earth, Marine and Environmental Sciences, The University of North Carolina at Chapel Hillgrid.10698.36, Chapel Hill, North Carolina, USA.
Garrett C SharpeEnvironment, Ecology and Energy Program, The University of North Carolina at Chapel Hillgrid.10698.36, Chapel Hill, North Carolina, USA.
Scott M GiffordDepartment of Earth, Marine and Environmental Sciences, The University of North Carolina at Chapel Hillgrid.10698.36, Chapel Hill, North Carolina, USA.ORCID 0000-0002-3222-9681
Alecia N SepterDepartment of Earth, Marine and Environmental Sciences, The University of North Carolina at Chapel Hillgrid.10698.36, Chapel Hill, North Carolina, USA.ORCID 0000-0002-9309-2930
Karen L VisickDepartment of Microbiology and Immunology, Loyola University Chicago, Maywood, Illinois, USA.ORCID 0000-0002-2400-2591
University of North Carolina at Chapel Hill · USLoyola University Chicago · US

Funding

Host-associated biofilm formation and dispersal mechanismsR35GM130355 · NIGMS · LOYOLA UNIVERSITY CHICAGO · PI Karen L Visick · 2019 to 2026
$3.5M
Genetic determinants of interbacterial competition during host colonizationR35GM137886 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Alecia Septer · 2020 to 2026
$2.6M
NIGMS NIH HHS R35 GM130355NIGMS NIH HHS R35 GM137886
6 · The paper itself

Abstract

The marine bacterium Vibrio fischeri efficiently colonizes its symbiotic squid host, Euprymna scolopes, by producing a transient biofilm dependent on the symbiosis polysaccharide (SYP).

Indexed as

Biofilms4-Aminobenzoic AcidAliivibrio fischeriAnimalsBacterial ProteinsCalciumCyclic GMPDecapodiformesGene Expression Regulation, BacterialPolysaccharides, BacterialSymbiosis4-Aminobenzoic AcidBacterial Proteinsbis(3',5')-cyclic diguanylic acidCalciumCyclic GMPPolysaccharides, Bacterialbiofilmscalcium signalingc-di-GMPcyclic nucleotidespABAsignal transductionVibrio fischeri

Identifiers

PMID34607467
PMCPMC8546588
OpenAlexW3204305700

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.