Evidence map›Paper›PMID 34607314›Full record

ArticleAging2021

Effects of periostin deficiency on kidney aging and lipid metabolism.

Jung Nam An, Hyoseon Kim, Eun Nim Kim, Ara Cho, Yeongeun Cho, Young Wook Choi, Jin Hyuk Kim, Seung Hee Yang, Bum Soon Choi, Chun Soo Lim and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Arachidonic acid in aging: New roles for old players.Journal of advanced research · 2025
    Review
  5. Constitutive activation mechanism of a class C GPCR.Nature structural & molecular biology · 2024
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Jung Nam AnDepartment of Internal Medicine, Hallym University Sacred Heart Hospital, Anyang, Gyeonggi-do, Korea.
Hyoseon KimDepartment of Applied Chemistry, Institute of Natural Science, Global Center for Pharmaceutical Ingredient Materials, Kyung Hee University, Yongin, Korea.
Eun Nim KimDepartment of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Ara ChoDepartment of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea.
Yeongeun ChoDepartment of Applied Chemistry, Institute of Natural Science, Global Center for Pharmaceutical Ingredient Materials, Kyung Hee University, Yongin, Korea.
Young Wook ChoiDepartment of Urology, College of Medicine, Chung-Ang University, Seoul, Korea.
Jin Hyuk KimDepartment of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea.
Seung Hee YangSeoul National University Kidney Research Institute, Seoul, Korea.
Bum Soon ChoiDepartment of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Chun Soo LimDepartment of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea.
Yon Su KimDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Kwang Pyo KimDepartment of Applied Chemistry, Institute of Natural Science, Global Center for Pharmaceutical Ingredient Materials, Kyung Hee University, Yongin, Korea.
Jung Pyo LeeDepartment of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea.
Seoul National University · KRKyung Hee University · KRCatholic University of Korea · KRSNUH SMG-SNU Boramae Medical Center · KRChung-Ang University · KRHallym University Sacred Heart Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periostin plays a crucial role in fibrosis, which is involved in kidney aging. A few studies have shown that lipid metabolism is involved in kidney aging. We investigated the role of periostin in lipid metabolism during kidney aging. Renal function, fibrosis, and inflammatory markers were studied using urine, blood, and tissue samples from wild-type (WT) C57BL/6 mice and

Indexed as

AgingAnimalsCell Adhesion MoleculesGene Expression RegulationKidneyLipid MetabolismMaleMiceMice, KnockoutRandom AllocationCell Adhesion MoleculesPostn protein, mouseagingkidneylipidlipidomicsperiostin

Identifiers

PMID34607314
PMCPMC8544301
OpenAlexW3202629480

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.