Evidence map›Paper›PMID 34606735›Full record

ArticleCell transplantation

Improvement of Heart Function After Transplantation of Encapsulated Stem Cells Induced with miR-1/Myocd in Myocardial Infarction Model of Rat.

Samaneh Khazaei, Masoud Soleimani, Seyed Hossein Ahmadi Tafti, Rouhollah Mehdinavaz Aghdam, Zohreh Hojati

Open access · goldAbstract read
In one paragraph

Article in Cell transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Samaneh KhazaeiDepartment of Cell and Molecular Biology, Faculty of Biological Science and Technology, Isfahan University, Isfahan, Iran.
Masoud SoleimaniTissue Engineering and Hematology Department, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Seyed Hossein Ahmadi TaftiResearch Center for Advanced Technologies in Cardiovascular Medicine, Tehran heart Center, Tehran University of Medical Sciences, Tehran, Iran.
Rouhollah Mehdinavaz AghdamSchool of Metallurgy & materials Engineering, College of Engineering, University of Tehran, Tehran, Iran.ORCID 0000-0003-2325-5121
Zohreh HojatiDepartment of Cell and Molecular Biology, Faculty of Biological Science and Technology, Isfahan University, Isfahan, Iran.ORCID 0000-0003-4831-0123
University of Isfahan · IRTarbiat Modares University · IRTehran University of Medical Sciences · IRUniversity of Tehran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular disease is one of the most common causes of death worldwide. Mesenchymal stem cells (MSCs) are one of the most common sources in cell-based therapies in heart regeneration. There are several methods to differentiate MSCs into cardiac-like cells, such as gene induction. Moreover, using a three-dimensional (3D) culture, such as hydrogels increases efficiency of differentiation. In the current study, mouse adipose-derived MSCs were co-transduced with lentiviruses containing microRNA-1 (

Indexed as

AnimalsCell DifferentiationDisease Models, AnimalMaleMesenchymal Stem Cell TransplantationMicroRNAsMyocardial InfarctionMyocardiumRatsRats, Sprague-DawleyMicroRNAsMIRN1 microRNA, rat3D culturecardiovascular diseasedifferentiationencapsulationmesenchymal stem cellsmiR-1transplantation

Identifiers

PMID34606735
PMCPMC8493326
OpenAlexW3203326370

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.