Evidence map›Paper›PMID 34606723›Full record

ArticleJournal of proteome research2021

Combined Molecular and Elemental Mass Spectrometry Approaches for Absolute Quantification of Proteomes: Application to the Venomics Characterization of the Two Species of Desert Black Cobras,

Juan J Calvete, Davinia Pla, Johannes Els, Salvador Carranza, Maik Damm, Benjamin-Florian Hempel, Elisa B O John, Daniel Petras, Paul Heiss, Ayse Nalbantsoy and 5 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of proteome research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Kinematics of strikes in venomous snakes.The Journal of experimental biology · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Venom characterization of the Brazilian Pampa snake Bothrops pubescens by top-down and bottom-up proteomics.Toxicon : official journal of the International Society on Toxinology · 2022
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 4 countries.

Juan J CalveteLaboratorio de Venómica Evolutiva y Traslational, Instituto de Biomedicina de Valencia, Consejo Superior de Investigaciones Científicas (CSIC), Jaume Roig 11, 46010 Valencia, Spain.ORCID 0000-0001-5026-3122
Davinia PlaLaboratorio de Venómica Evolutiva y Traslational, Instituto de Biomedicina de Valencia, Consejo Superior de Investigaciones Científicas (CSIC), Jaume Roig 11, 46010 Valencia, Spain.
Johannes ElsEnvironment and Protected Areas Authority, 82828 Sharjah, United Arab Emirates.
Salvador CarranzaInstitute of Evolutionary Biology, CSIC-Universitat Pompeu Fabra, 08003 Barcelona, Spain.
Maik DammDepartment of Chemistry, Technische Universität Berlin, 10623 Berlin, Germany.
Benjamin-Florian HempelDepartment of Chemistry, Technische Universität Berlin, 10623 Berlin, Germany.
Elisa B O JohnCenter of Biotechnology, Universidade Federal do Rio Grande do Sul, CEP 91501-970 Porto Alegre, RS, Brazil.
Daniel PetrasCMFI Cluster of Excellence, Interfaculty Institute of Microbiology and Medicine, University of Túbingen, 72076 Tübingen, Germany.
Paul HeissDepartment of Chemistry, Technische Universität Berlin, 10623 Berlin, Germany.
Ayse NalbantsoyDepartment of Bioengineering, Faculty of Engineering, Ege University, 35100 Bornova, Izmir, Turkey.
Bayram GöçmenZoology Section, Department of Biology, Faculty of Science, Ege University, 35100 Bornova, Izmir, Turkey.
Roderich D SüssmuthDepartment of Chemistry, Technische Universität Berlin, 10623 Berlin, Germany.
Francisco Calderón-CelisDepartment of Physical and Analytical Chemistry, University of Oviedo, 33006 Oviedo, Spain.
Alicia Jiménez NostiDepartment of Physical and Analytical Chemistry, University of Oviedo, 33006 Oviedo, Spain.
Jorge Ruiz EncinarDepartment of Physical and Analytical Chemistry, University of Oviedo, 33006 Oviedo, Spain.ORCID 0000-0001-6245-5770
Technische Universität Berlin · DEUniversidad de Oviedo · ESConsejo Superior de Investigaciones Científicas · ESEge University · TRUniversidade Federal do Rio Grande do Sul · BRUniversitat Pompeu Fabra · ESUniversity of Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a novel hybrid, molecular and elemental mass spectrometry (MS) setup for the absolute quantification of snake venom proteomes shown here for two desert black cobra species within the genus

Indexed as

ElapidaeElapid VenomsProteomeAnimalsProteomicsTandem Mass SpectrometryElapid VenomsProteomeabsolute quantification of venom proteomecombined top-down and bottom-up venomicsdesert black cobrahybrid elemental and molecular mass spectrometrysnake venomicsWalterinnesia aegyptiaWalterinnesia morgani

Identifiers

PMID34606723
PMCPMC8576837
OpenAlexW3204346197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.