Evidence map›Paper›PMID 34606693›Full record

ArticlePediatric pulmonology2022

Understanding the environmental factors related to the decrease in Pediatric Emergency Department referrals for acute asthma during the SARS-CoV-2 pandemic.

Arianna Dondi, Ludovica Betti, Claudio Carbone, Ada Dormi, Marco Paglione, Matteo Rinaldi, Maurizio Gualtieri, Fabiana Scotto, Vanes Poluzzi, Marianna Fabi and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Pediatric pulmonology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. The influence of air pollutants on the risk of emergency department presentations of infants with bronchiolitis in an European air quality hotspot.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
    Observational
  4. Article
  5. A Review of the Role of Pollen in COVID-19 Infection.International journal of environmental research and public health · 2023
    Review
  6. Review
  7. Article
  8. Allergic diseases and immunodeficiencies in children, lessons learnt from COVID-19 pandemic by 2022: A statement from the EAACI-section on pediatrics.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2022
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Arianna DondiPediatric Emergency Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Sant'Orsola University Hospital, Bologna, Italy.ORCID 0000-0002-7516-243X
Ludovica BettiSpecialty School of Pediatrics-Alma Mater Studiorum, University of Bologna, Bologna, Italy.ORCID 0000-0001-8416-8764
Claudio CarboneItalian National Agency for New Technologies, Energy and Sustainable Economic Development (ENEA), Bologna, Italy.ORCID 0000-0002-3025-8868
Ada DormiDepartment of Medical and Surgical Science (DIMEC), University of Bologna, Bologna, Italy.
Marco PaglioneItalian National Research Council-Institute of Atmospheric Sciences and Climate (CNR-ISAC), Bologna, Italy.ORCID 0000-0002-4423-2570
Matteo RinaldiItalian National Research Council-Institute of Atmospheric Sciences and Climate (CNR-ISAC), Bologna, Italy.ORCID 0000-0001-6543-4000
Maurizio GualtieriItalian National Agency for New Technologies, Energy and Sustainable Economic Development (ENEA), Bologna, Italy.ORCID 0000-0002-9318-2709
Fabiana ScottoAir Quality Thematic Regional Center-Agency for Prevention, Environmental and Energy of Emilia-Romagna (Arpae), Bologna, Italy.
Vanes PoluzziAir Quality Thematic Regional Center-Agency for Prevention, Environmental and Energy of Emilia-Romagna (Arpae), Bologna, Italy.
Marianna FabiPediatric Emergency Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Sant'Orsola University Hospital, Bologna, Italy.ORCID 0000-0002-2727-3506
Marcello LanariPediatric Emergency Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Sant'Orsola University Hospital, Bologna, Italy.
IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola · ITAgenzia Regionale Prevenzione e Ambiente della Regione Emilia-Romagna · ITInstitute of Atmospheric Sciences and Climate · ITNational Agency for New Technologies, Energy and Sustainable Economic Development · ITUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLockdown measures during the SARS-CoV-2 pandemic determined radical changes to behavioral and social habits, that were reflected by a reduction in the transmission of respiratory pathogens and in anthropogenic atmospheric emissions.

objectiveThis ecological study aims to provide a descriptive evaluation on how restrictive measures during the SARS-CoV-2 pandemic impacted Pediatric Emergency Department (PED) referrals for asthma exacerbations, and their potentially associated environmental triggers in Bologna, a densely populated urban area in Northern Italy.

methodsFiles of children evaluated for acute asthma during 2015 to 2020 at the PED of Sant'Orsola University Hospital of Bologna were retrospectively reviewed. Historical daily concentration records of particulate (PM

resultsIn 2020, asthma-related PED referrals decreased compared to referral rates of the previous 5 years (p < 0.01). This effect was particularly marked during the first lockdown period (March to May), when the drastic drop in PED referrals was associated with a reduction of high-priority cases up to 85% and by 54%, on average. A concomitant reduction in the concentrations of traffic-related air pollutants was observed in the range of 40%-60% (p < 0.01).

conclusionsThe lower rate of asthma exacerbations in childhood was in this study paralleled with reduced TRAP levels during the pandemic. Synergic interactions of the multiple consequences of lockdowns likely contributed to the reduced exacerbations, including decreased exposure to ambient pollutants and fewer respiratory infections, identified as the most important factor in the literature.

Indexed as

Air PollutantsAir PollutionAsthmaCOVID-19Communicable Disease ControlEmergency Service, HospitalEnvironmental MonitoringHumansPandemicsParticulate MatterReferral and ConsultationRetrospective StudiesSARS-CoV-2Air PollutantsParticulate Matterallergensasthma exacerbationsoxidative stresstraffic-related air pollution

Identifiers

PMID34606693
PMCPMC8661783
OpenAlexW3204277010

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.