Evidence map›Paper›PMID 34606691›Full record

Observational studyClinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery2022

Acute paediatric mastoiditis in the UK before and during the COVID-19 pandemic: A national observational study.

Matthew E Smith, G Huw Jones, John C Hardman, Jaya Nichani, Sadie Khwaja, INTEGRATE (The UK ENT Trainee Research Network) UK Acute Paediatric Mastoiditis Audit Collaborators, Iain A Bruce, Peter Rea

Erratum issuedOpen access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 33 citations in OpenAlex.

  1. Epidemiological evolution of acute mastoiditis in children after COVID-19 pandemic.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
  2. Article
  3. Shifting patterns of acute otitis media and mastoiditis through COVID-19 Era: analysis of pre-pandemic, pandemic, and post-pandemic dynamics.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
  4. Observational
  5. Article
  6. Increase in acute mastoiditis at the end of the COVID-19 pandemic.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Article
  7. Article
  8. Corrigendum.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2022
    Article
  9. Acute paediatric mastoiditis in the UK before and during the COVID-19 pandemic: A national observational study.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2022
    Observational
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 1 country.

Matthew E SmithDepartment of Otolaryngology, Salford Royal Hospital, Manchester, UK.ORCID 0000-0001-8147-1549
G Huw JonesDepartment of Otolaryngology, Gloucestershire Hospitals NHS Foundation Trust, Gloucester, UK.
John C HardmanThe Head and Neck Unit, The Royal Marsden Hospital, London, UK.ORCID 0000-0002-6591-5119
Jaya NichaniPaediatric Otolaryngology Department, Royal Manchester Children's Hospital, University of Manchester, UK.
Sadie KhwajaDepartment of Otolaryngology, Manchester University Foundation Trust, Manchester, UK.
INTEGRATE (The UK ENT Trainee Research Network) UK Acute Paediatric Mastoiditis Audit Collaborators
Iain A BrucePaediatric ENT Department, Royal Manchester Children's Hospital, MAHSC, University of Manchester, UK.
Peter ReaDepartment of Otolaryngology, Leicester Royal Infirmary, Leicester, UK.
Gloucestershire Hospitals NHS Foundation Trust · GBLeicester Royal Infirmary · GBManchester Academic Health Science Centre · GBManchester University NHS Foundation Trust · GBRoyal Marsden Hospital · GBSalford Royal Hospital · GBUniversity of Manchester · GB

Funding

ENTUK (The professional membership body for Ear Nose and Throat surgery in the UK) NAThe British Association for Paediatric Otolaryngology NAThe British Society of Otology NAThe North West ENT Research Fund NA
6 · The paper itself

Abstract

objectivesTo explore the impact of COVID-19 on the management and outcomes of acute paediatric mastoiditis across the UK.

designNational retrospective and prospective audit.

setting48 UK secondary care ENT departments.

participantsConsecutive children aged 18 years or under, referred to ENT with a clinical diagnosis of mastoiditis.

main outcome measuresCases were divided into Period 1 (01/11/19-15/03/20), before the UK population were instructed to reduce social contact, and Period 2 (16/03/20-30/04/21), following this. Periods 1 and 2 were compared for population variables, management and outcomes. Secondary analyses compared outcomes by primary treatment (medical/needle aspiration/surgical).

results286 cases met criteria (median 4 per site, range 0-24). 9.4 cases were recorded per week in period 1 versus 2.0 in period 2, with no winter increase in cases in December 2020-Febraury 2021. Patient age differed between periods 1 and 2 (3.2 vs 4.7 years respectively, p < 0.001). 85% of children in period 2 were tested for COVID-19 with a single positive test. In period, 2 cases associated with P. aeruginosa significantly increased. 48.6% of children were scanned in period 1 vs 41.1% in period 2. Surgical management was used more frequently in period 1 (43.0% vs 24.3%, p = 0.001). Treatment success was high, with failure of initial management in 6.3%, and 30-day re-admission for recurrence in 2.1%. The adverse event rate (15.7% overall) did not vary by treatment modality or between periods 1& 2.

conclusionThe COVID-19 pandemic led to a significant change in the presentation and case mix of acute paediatric mastoiditis in the UK.

Indexed as

Acute DiseaseAdolescentChildChild, PreschoolCOVID-19FemaleHumansIncidenceInfantMaleMastoiditisPandemicsProspective StudiesRetrospective StudiesSARS-CoV-2Seasonsacute mastoiditisantibioticCOVIDpaediatricsurgery

Identifiers

PMID34606691
PMCPMC8652842
OpenAlexW3204333489

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.