Evidence map›Paper›PMID 34606646›Full record

ArticleJournal of clinical laboratory analysis2021

Responses of CD27

Chenshuang Lei, Qinhua Yu, Hong Wang, JieJing Liu, Sufeng Chen, Zhao Zhao, Liannv Qiu

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical laboratory analysis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Responses of CD27Journal of clinical laboratory analysis · 2021
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Chenshuang LeiDepartment of Clinical Laboratory, Zhejiang Chinese Medical University, Hangzhou, China.ORCID https://orcid.org/0000-0002-2325-7509
Qinhua YuDepartment of Clinical Laboratory, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, China.
Hong WangDepartment of infection, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, China.
JieJing LiuDepartment of Clinical Laboratory, Wenzhou Medical University, Wenzhou, China.
Sufeng ChenDepartment of Clinical Laboratory, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, China.
Zhao ZhaoDepartment of Clinical Laboratory, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, China.
Liannv QiuDepartment of Clinical Laboratory, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, China.
Zhejiang Provincial People's Hospital · CNWenzhou Medical University · CNZhejiang Chinese Medical University · CN

Funding

Natural Science Foundation of Zhejiang Province Y18H200014
6 · The paper itself

Abstract

backgroundHumoral immunity is thought to play a central role in mediating the immunopathogenesis of dengue virus (DENV) infection; however, the B-cell responses elicited by primary DENV2 infection are incompletely understood. Follicular helper T cells (Tfh) are important to promote B-cell activation and differentiation.

methodsThe present study analyzed the detailed dynamic changes of circulating B-cell subsets and Tfh (cTfh) using flow cytometry to explore their responses to DENV2 infection.

resultsThirty-six patients with DENV2 and 21 healthy individuals were included. The results showed that CD27

conclusionOverall, these results provide insights into the DENV2-elicited B-cell response and revealed previously unidentified CD24

Indexed as

B-Lymphocytes, RegulatoryDengueAdolescentAdultAgedAged, 80 and overAntigens, CDDengue VirusFemaleFlow CytometryHumansMaleMiddle AgedT Follicular Helper CellsYoung AdultAntigens, CDB-cell subsetsdengue feverflow cytometryfollicular helper T cells

Identifiers

PMID34606646
PMCPMC8605120
OpenAlexW3201831168

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.