Evidence map›Paper›PMID 34606505›Full record

Observational studyPloS one2021

Better health-related quality of life in kidney transplant patients compared to chronic kidney disease patients with similar renal function.

Jung-Hwa Ryu, Tai Yeon Koo, Han Ro, Jang-Hee Cho, Myung-Gyu Kim, Kyu Ha Huh, Jae Berm Park, Sik Lee, Seungyeup Han, Jayoun Kim and 3 more

Open access · goldAbstract readComparative StudyMulticenter StudyObservational Study
In one paragraph

Observational study in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Health-related quality of life in kidney transplant recipients: association with graft function and comparison to patients on dialysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 10 institutions in 1 country.

Jung-Hwa RyuTransplantation Center, Seoul National University Hospital, Seoul, Republic of Korea.
Tai Yeon KooNephrology, Seongnam Citizens Medical Center, Seongnam, Republic of Korea.
Han RoDepartment of Internal Medicine, Gachon University Gil Medical Center, Incheon, Republic of Korea.
Jang-Hee ChoDepartment of Internal Medicine, Kyungpook National University Hospital, Daegu, Republic of Korea.
Myung-Gyu KimDepartment of Internal Medicine, Korea University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0001-8807-2452
Kyu Ha HuhDepartment of Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea.
Jae Berm ParkDepartment of Surgery, Seoul Samsung Medical Center, Sungkyunkwan University, Seoul, Republic of Korea.
Sik LeeDepartment of Internal Medicine, Chonbuk National University Hospital, Jeonju, Republic of Korea.
Seungyeup HanDepartment of Internal Medicine, Keimyung University, Dongsan Medical Center, Daegu, Republic of Korea.ORCID 0000-0002-7561-6534
Jayoun KimMedical Research Collaborating Center, Seoul National University Hospital, Seoul, Republic of Korea.
Kook-Hwan OhDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
Jaeseok YangDivision of Nephrology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0002-5378-7797
KNOW-KT Study group
Yonsei University · KREwha Womans University · KRGachon University Gil Medical Center · KRJeonbuk National University Hospital · KRKeimyung University Dongsan Medical Center · KRKorea University · KRKyungpook National University Hospital · KRSamsung Medical Center · KRSeoul National University · KRSeoul National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal functional deterioration is associated with physical and mental burdens for kidney transplant (KT) and chronic kidney disease (CKD) patients. However, the change in health-related quality of life (HRQOL) over time in KT patients compared to that of native CKD patients has not been evaluated. We addressed this issue using KT patients registered in the KNOW-KT cohort study and patients at CKD stage 1-3 registered in the KNOW-CKD cohort study. HRQOL scores were assessed using the Kidney Disease Quality of Life Short Form at baseline, 2-, and 4-years follow-up in 842 KT patients and at baseline and 5-year follow-up in 1,355 CKD patients. SF-36 scores declined at the 4-year follow-up, whereas CKD-targeted scores showed no change in the KT group. In contrast, CKD-targeted scores as well as SF-36 scores were decreased at the 5-year follow-up in CKD patients. When prognostic factors were analyzed for longitudinal HRQOL data over time, renal functions, diabetes, cardiovascular and cerebrovascular diseases, hemoglobin level, marital status, income, employment, and health care were significant prognostic factors. Furthermore, KT was an independent prognostic factor for better HRQOL. These results highlight that KT can offer a better HRQOL than that of CKD patients, even when renal function is similar.

Indexed as

Kidney TransplantationQuality of LifeTransplant RecipientsAdultAgedCerebrovascular DisordersComorbidityDelivery of Health CareDiabetes MellitusEmploymentFemaleFollow-Up StudiesHemoglobinsHumansIncomeKidneyHemoglobins

Identifiers

PMID34606505
PMCPMC8489710
OpenAlexW3128047093

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.