Evidence map›Paper›PMID 34606371›Full record

ArticleJournal of bacteriology2021

Identification of a Novel Pyruvyltransferase Using

Derek H Wells, Nicolette F Goularte, Melanie J Barnett, Lynette Cegelski, Sharon R Long

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.7field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Derek H Wells *Department of Biology, Stanford Universitygrid.168010.e, Stanford, California, USA.
Nicolette F Goularte *Department of Structural Biology, Stanford Universitygrid.168010.e, Stanford, California, USA.ORCID 0000-0001-6557-9349
Melanie J BarnettDepartment of Biology, Stanford Universitygrid.168010.e, Stanford, California, USA.ORCID 0000-0003-3350-278X
Lynette CegelskiDepartment of Chemistry, Stanford Universitygrid.168010.e, Stanford, California, USA.ORCID 0000-0002-0978-1814
Sharon R LongDepartment of Structural Biology, Stanford Universitygrid.168010.e, Stanford, California, USA.
Stanford University · US

Funding

Control of Symbiotic Gene Expression in Sinorhizobium melilotiR01GM093628 · NIGMS · STANFORD UNIVERSITY · PI LONG, SHARON R · 2010 to 2017
$7.0M
NIGMS NIH HHS R01 GM093628NIH HHS GM093628
6 · The paper itself

Abstract

The alphaproteobacterium Sinorhizobium meliloti secretes two acidic exopolysaccharides (EPSs), succinoglycan (EPSI) and galactoglucan (EPSII), which differentially enable it to adapt to a changing environment. Succinoglycan is essential for invasion of plant hosts and, thus, for the formation of nitrogen-fixing root nodules. Galactoglucan is critical for population-based behaviors such as swarming and biofilm formation and can facilitate invasion in the absence of succinoglycan on some host plants. The biosynthesis of galactoglucan is not as completely understood as that of succinoglycan. We devised a pipeline to identify putative pyruvyltransferase and acetyltransferase genes, construct genomic deletions in strains engineered to produce either succinoglycan or galactoglucan, and analyze EPS from mutant bacterial strains. EPS samples were examined by

Indexed as

Bacterial ProteinsGalactansGene Expression Regulation, BacterialGene Expression Regulation, EnzymologicGlucansHumansMagnetic Resonance SpectroscopyMutationPolysaccharides, BacterialSinorhizobium melilotiTransferasesBacterial ProteinsGalactansgalactoglucanGlucansPolysaccharides, BacterialsuccinoglycanTransferasesexopolysaccharidenuclear magnetic resonanceSinorhizobium meliloti

Identifiers

PMID34606371
PMCPMC8604072
OpenAlexW3204572875

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.