Evidence map›Paper›PMID 34606368›Full record

ArticleInfection and immunity2022

Evolutionary Insights into the Microneme-Secreted, Chitinase-Containing High-Molecular-Weight Protein Complexes Involved in

Hargobinder Kaur, M Andreina Pacheco, Laine Garber, Ananias A Escalante, Joseph M Vinetz

Abstract read
In one paragraph

Article in Infection and immunity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Frontiers in cellular and infection microbiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hargobinder KaurSection of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
M Andreina PachecoDepartment of Biology, Institute for Genomics and Evolutionary Medicine (iGEM), Temple Universitygrid.264727.2, Philadelphia, Pennsylvania, USA.
Laine GarberSection of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
Ananias A EscalanteDepartment of Biology, Institute for Genomics and Evolutionary Medicine (iGEM), Temple Universitygrid.264727.2, Philadelphia, Pennsylvania, USA.
Joseph M VinetzSection of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0001-8344-2004

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Sugar-feeding behavior of the malaria vector Nyssorhynchus darlingi and development of effective attractive toxic sugar baits (ATSB) to increase intervention success in PeruU19AI089681 · NIAID · YALE UNIVERSITY · PI CASTRO, MARCIA C. · 2010 to 2023
$20.1M
MOLECULAR TARGETS OF BLOCKING MALARIA TRANSMISSIONR01AI045999 · NIAID · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI VINETZ, JOSEPH M. · 2000 to 2010
$3.2M
Proteomics of the Plasmodium OokineteR21AI053781 · NIAID · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI VINETZ, JOSEPH M. · 2002 to 2003
$426k
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI45999NCATS NIH HHS UL1 TR001863NIAID NIH HHS R01 AI045999NIAID NIH HHS R21 AI053781NIAID NIH HHS U19 AI089681
6 · The paper itself

Abstract

While general mechanisms by which

Indexed as

Host-Parasite InteractionsAnimalsBiological EvolutionChitinasesCulicidaeDigestive SystemMicronemeModels, BiologicalModels, MolecularMolecular WeightMultiprotein ComplexesPhylogenyPlasmodiumProtein ConformationSpecies SpecificityStructure-Activity RelationshipChitinasesMultiprotein Complexesarthropod vectorsevolutionmalariaookinetePlasmodium

Identifiers

PMID34606368
PMCPMC8788677

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.