Evidence map›Paper›PMID 34606353›Full record

ArticleHealth affairs (Project Hope)2021

Risk And Resilience Factors Influencing Postpartum Depression And Mother-Infant Bonding During COVID-19.

Sara L Kornfield, Lauren K White, Rebecca Waller, Wanjiku Njoroge, Ran Barzilay, Barbara H Chaiyachati, Megan M Himes, Yuheiry Rodriguez, Valerie Riis, Keri Simonette and 2 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Health affairs (Project Hope), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06576323 (An Intervention Mapping Approach to Closing the Gap in Maternal OUD and Infant NAS Care), which is not on this map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06576323 narecruitingnot on this mapstarted 2024, after this paper: background citation

An Intervention Mapping Approach to Closing the Gap in Maternal OUD and Infant NAS Care

TypeinterventionalSponsorUniversity of PennsylvaniaRan2024 to 2027Enrolled50ConditionsOpioid Use Disorder, Neonatal Abstinence SyndromeArmsAn implementation model for co-located Medications for Opioid Use Disorder (MOUD) prescription in the NICU
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Leveraging Machine Learning to Uncover Ethnic-Specific Predictors of Maternal Postpartum Depression.Prevention science : the official journal of the Society for Prevention Research · 2026
    Article
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  10. Evidence for missed cases of postpartum depression based on paediatric clinical care screenings.The British journal of psychiatry : the journal of mental science · 2025
    Article
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  14. Observational
  15. Role of self-criticism in postpartum mental health: a network analysis.Psicologia, reflexao e critica : revista semestral do Departamento de Psicologia da UFRGS · 2024
    Article
  16. Article
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  19. Article
  20. Risk and Resilience Measures Related to Psychopathology in Youth.Child psychiatry and human development · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Sara L KornfieldSara L. Kornfield is an assistant professor in the Penn Center for Women's Behavioral Wellness, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, in Philadelphia, Pennsylvania. Kornfield and Lauren K. White are co-first authors.
Lauren K WhiteLauren K. White (WHITELK@chop.edu) is a research scientist in the Lifespan Brain Institute, Children's Hospital of Philadelphia and Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania. White and Sara L. Kornfield are co-first authors.
Rebecca WallerRebecca Waller is an assistant professor in the Department of Psychology, University of Pennsylvania.
Wanjiku NjorogeWanjiku Njoroge is an assistant professor in the Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania.
Ran BarzilayRan Barzilay is an assistant professor in the Lifespan Brain Institute, Children's Hospital of Philadelphia and Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania.
Barbara H ChaiyachatiBarbara H. Chaiyachati is an associate fellow in the Lifespan Brain Institute, Children's Hospital of Philadelphia and Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania.
Megan M HimesMegan M. Himes is a research assistant in the Lifespan Brain Institute, Children's Hospital of Philadelphia and Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania.
Yuheiry RodriguezYuheiry Rodriguez is a study coordinator in the Department of Psychology, University of Pennsylvania.
Valerie RiisValerie Riis is the director of operations, Maternal and Child Health Research Center, Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania.
Keri SimonetteKeri Simonette is a clinical research coordinator at Jefferson Health, in Philadelphia, Pennsylania. She was a project manager with the Maternal Child Health Research Center, Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, when this work was performed.
Michal A ElovitzMichal A. Elovitz is a professor in the Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania.
Raquel E GurRaquel E. Gur is a professor in the Lifespan Brain Institute, Children's Hospital of Philadelphia and Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania.
Children's Hospital of Philadelphia · USUniversity of Pennsylvania · USAria - Jefferson Health · USIndiana University of Pennsylvania · USUniversidad Nacional Experimental Simón Rodríguez · VE

Funding

The role of host-microbial interactions in altering preterm birth risk among black womenR01NR014784 · NINR · UNIVERSITY OF PENNSYLVANIA · PI ELOVITZ, MICHAL AVIVA · 2013 to 2024
$6.4M
SCHIZOPHRENIA: A NEUROPSYCHIATRIC PERSPECTIVET32MH019112 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI GUR, RAQUEL E · 1990 to 2024
$6.2M
Evolution of Psychosis in Youth: Multimodal Risk and Resilience MarkersR01MH119219 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI GUR, RAQUEL E, GUR, RUBEN C. · 2019 to 2023
$3.8M
Mechanisms of resilience to developmental stress in children and adolescents.K23MH120437 · NIMH · CHILDREN'S HOSP OF PHILADELPHIA · PI BARZILAY, RAN · 2019 to 2022
$775k
NIMH NIH HHS K23 MH120437NIMH NIH HHS R01 MH119219NIMH NIH HHS T32 MH019112NINR NIH HHS R01 NR014784
6 · The paper itself

Abstract

Acute stress during pregnancy can have adverse effects on maternal health and increase the risk for postpartum depression and impaired mother-infant bonding. The COVID-19 pandemic represents an acute environmental stressor during which it is possible to explore risk and resilience factors that contribute to postpartum outcomes. To investigate prenatal risk and resilience factors as predictors of postpartum depression and impaired mother-infant bonding, this study recruited a diverse cohort of 833 pregnant women from an urban medical center in Philadelphia, Pennsylvania, and assessed them once during pregnancy in the early phase of the COVID-19 pandemic (April-July 2020) and again at approximately twelve weeks postpartum. Adverse childhood experiences, prenatal depression and anxiety, and COVID-19-related distress predicted a greater likelihood of postpartum depression. Prenatal depression was the only unique predictor of impaired maternal-infant bonding after postpartum depression was controlled for. Women reporting greater emotion regulation, self-reliance, and nonhostile relationships had healthier postpartum outcomes. Policies to increase the number of nonspecialty providers providing perinatal mental health services as well as reimbursement for integrated care and access to mental health screening and care are needed to improve lifelong outcomes for women and their children.

Indexed as

COVID-19Depression, PostpartumChildFemaleHumansInfantMothersPandemicsPhiladelphiaPregnancySARS-CoV-2

Identifiers

PMID34606353
PMCPMC9351691
OpenAlexW3204194449

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.