ArticleActa neurologica Belgica2022
Pediatric cerebral sinus venous thrombosis: clinical characterization of a Portuguese cohort.
Article in Acta neurologica Belgica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
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Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Efficacy and safety of anticoagulation for pediatric cerebral sinovenous thrombosis: systematic review and meta-analysis.Research and practice in thrombosis and haemostasis · 2026Pooled it
- American Society of Hematology/International Society on Thrombosis and Haemostasis 2024 updated guidelines for treatment of venous thromboembolism in pediatric patients.Blood advances · 2025Guideline
- Cerebral Venous Thrombosis:Current Status and Challenges.Brain and behavior · 2025Review
- Congenital disorders of glycosylation type 1A associated with cerebral hemorrhagic infarction: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Commentary: Characteristics and Outcomes of Children with Cerebral Sinus Venous Thrombosis.Neurocritical care · 2023Article
- Study of 52 Pediatric Patients Who Required 78 Hospital Admissions for Cerebral Venous Sinus Thrombosis from 2013 to 2020 Using Data from the Polish National Health Fund Registry.Medical science monitor : international medical journal of experimental and clinical research · 2023Article
- Case report: cerebral venous sinus thrombosis and pulmonary embolism as the initial presentation in a child with asymptomatic primary nephrotic syndrome.Frontiers in pediatrics · 2023Article
- Risk factors in pediatric cerebral sinovenous thrombosis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Article
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Authors and funding
9 authors.
Funding
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Abstract
introductionPediatric cerebral sinus venous thrombosis (CSVT) is a rare entity. Risk factors differ from the adults, and treatment is not consensual. With this work, we aimed to characterize a pediatric cohort from two Portuguese tertiary centers.
methodsAll patients under 18 years old with confirmed CSVT admitted between 2006 and 2019 were retrospectively included. Demographics, clinical presentation, workup, and follow-up were evaluated.
resultsFifty-three patients were included, 29 were male (54.7%). Median age was 5 years (IQR 11.08, range 0-17 years old). Headache, seizures and impairment of consciousness were the most frequent manifestations. A risk factor was identified in 90.6% (n = 48), mostly infections (43.8%; n = 21). CNS complications were comprised of hemorrhage, venous infarction, hydrocephalus and edema. Treatment included anticoagulation in 36 patients (67.9%), and there were no recurrences on follow-up. Prognosis was favorable, with most patients presenting no or only slight disability comparing to same age and sex children, on the follow-up. DISCUSSION: In this cohort, impairment of consciousness was the most frequent clinical presentation and infections were the most frequent risk factors. The outcome was mainly favorable, with most patients presenting none or mild disability and without recurrences on follow-up. Studies are needed to define the criteria for anticoagulation and its recommended duration in children.
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