Evidence map›Paper›PMID 34605992›Full record

ArticleArchives of gynecology and obstetrics2022

Lifting the veil of secrecy: maternal and neonatal outcome of oocyte donation pregnancies in Germany.

J Altmann, J Kummer, F Herse, L Hellmeyer, D Schlembach, W Henrich, A Weichert

Abstract read
In one paragraph

Article in Archives of gynecology and obstetrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

J AltmannDepartment of Obstetrics, Charité-Universitätsmedizin, 10117, Berlin, Germany. Judith.altmann@charite.de.ORCID 0000-0003-2065-5058
J KummerDepartment of Obstetrics and Gynecology, Vivantes Hospital Friedrichshain, Berlin, Germany.
F HerseBerlin Institute of Health, Berlin, Germany.
L HellmeyerDepartment of Obstetrics and Gynecology, Vivantes Hospital Friedrichshain, Berlin, Germany.
D SchlembachClinic of Obstetric Medicine, Vivantes Hospital Neukoelln, Berlin, Germany.
W HenrichDepartment of Obstetrics, Charité-Universitätsmedizin, 10117, Berlin, Germany.
A WeichertDepartment of Obstetrics, Charité-Universitätsmedizin, 10117, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn Germany, performing fertility procedures involving oocyte donation is illegal, as stated by the Embryo Protection Law. Nonetheless, in our clinical routine we attend to a steadily rising number of pregnant women, who have sought oocyte donation abroad. Due to the legal circumstances many women opt to keep the origin of their pregnancy a secret. However, studies have shown, that oocyte donation is an independent risk factor for the development of pregnancy complications, such as preeclampsia.

objectiveThe aim of this study is to evaluate maternal and neonatal outcomes of oocyte donation pregnancies in three large obstetric care units in Berlin, Germany.

methodsWe retrospectively analyzed all available medical data on oocyte donation pregnancies at Charité University hospital, Vivantes Hospital Friedrichshain, and Neukoelln in the German capital.

resultsWe included 115 oocyte donation (OD) pregnancies in the present study. Our data are based on 62 singleton, 44 twin, 7 triplet, and 2 quadruplet oocyte donation pregnancies. According to our data, oocyte donation pregnancies are associated with a high risk of adverse maternal and fetal outcome, i.e., hypertension in pregnancy, preterm delivery, Cesarean section as mode of delivery, and increased peripartum hemorrhage.

conclusionAlthough oocyte donation is prohibited by German law, many couples go abroad to seek reproductive measures using oocyte donation after former treatment options have failed. OD pregnancies are associated with a high risk of preeclampsia, C-section as mode of delivery, and peripartum hemorrhage. Detailed knowledge of the associated risks is of utmost importance to both the patient and the treating physician and midwife.

Indexed as

Oocyte DonationPre-EclampsiaCesarean SectionConfidentialityFemaleFertilization in VitroHumansPregnancyPregnancy OutcomeRetrospective StudiesEgg-donationOocyte-donationPeripartum hemorrhagePreeclampsiaPregnancy risks

Identifiers

PMID34605992
PMCPMC9300520

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