Evidence map›Paper›PMID 34605853›Full record

ArticleJAMA internal medicine2021

Acute Myocarditis Following COVID-19 mRNA Vaccination in Adults Aged 18 Years or Older.

Anthony Simone, John Herald, Aiyu Chen, Neil Gulati, Albert Yuh-Jer Shen, Bruno Lewin, Ming-Sum Lee

Registry-linked trialAbstract read
In one paragraph

Article in JAMA internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05280158 (Phase I/II, Open-Label Dose-Finding Trial of High-Dose mRNA-1273 Booster for Lung Transplant Recipients), which is not on this map. Cited by 74 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05280158 phase1 / phase2terminatednot on this mapstarted 2022, after this paper: background citation

Phase I/II, Open-Label Dose-Finding Trial of High-Dose mRNA-1273 Booster for Lung Transplant Recipients

TypeinterventionalSponsorUniversity of California, Los AngelesRan2022 to 2023Enrolled19ConditionsLung Transplant Recipient, SARS-CoV-2, ImmunosuppressionArmsmRNA-1273 (Moderna COVID-19 vaccine)
3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 9 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. COVID-19 vaccine induced myocarditis in young males: A systematic review.European journal of clinical investigation · 2023
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Myocarditis after RNA-based vaccines for coronavirus.International journal of cardiology · 2022
    Pooled it
  9. Pooled it
  10. Review
  11. Observational
  12. Myocarditis-Associated Cardiogenic Shock: A Nationwide Multicenter Study.Journal of the American Heart Association · 2025
    Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Review

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Anthony SimoneDepartment of Cardiology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, California.
John HeraldDepartment of Cardiology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, California.
Aiyu ChenDepartment of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, California.
Neil GulatiDepartment of Cardiology, Kaiser Permanente Orange County Medical Center, Irvine, California.
Albert Yuh-Jer ShenDepartment of Cardiology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, California.
Bruno LewinDepartment of Family Medicine, Kaiser Permanente Los Angeles Medical Center, Los Angeles, California.
Ming-Sum LeeDepartment of Cardiology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, California.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

2019-nCoV Vaccine mRNA-1273AdolescentAdultAutoantigensBNT162 VaccineCaliforniaCOVID-19COVID-19 VaccinesFemaleHumansMaleMyocarditisRNA, MessengerSARS-CoV-2Vaccination2019-nCoV Vaccine mRNA-1273AutoantigensBNT162 VaccineCOVID-19 VaccinesRNA, Messenger

Identifiers

PMID34605853
PMCPMC8491129

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.