ArticleActa ophthalmologica2022
Distribution and association of visual impairment with myopic maculopathy across age groups among highly myopic eyes - based on the new classification system (ATN).
Article in Acta ophthalmologica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 17 citations in OpenAlex.
- Association of macular outward scleral height with axial length, macular choroidal thickness and morphologic characteristics of the optic disc in Chinese adults.Eye (London, England) · 2024Trial
- Spontaneous Pathologic Myopia and Contributing Factors in Nonhuman Primate Models.Translational vision science & technology · 2026Article
- Macular changes among adult Egyptian patients with pathological myopia.International journal of ophthalmology · 2026Article
- Development and validation of machine learning for pathological changes in high myopia patients with tessellated fundus: a cross-sectional study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Clinical characteristics and treatment outcomes of bilateral myopic macular neovascularization in high myopic patients.Acta ophthalmologica · 2025Article
- Development and Validation of a Diagnostic Nomogram for Pathologic Myopia in Patients with High Myopia and Tessellated Fundus: A Cross-Sectional Study.Risk management and healthcare policy · 2025Article
- Investigation of choroidal vascular alterations in eyes with myopia using ultrawidefield optical coherence tomography angiography.BMJ open ophthalmology · 2024Article
- Relationship Between Early-Life Factors and Self-Reported Age at Myopia Onset: A Study Based on a Sample of Chinese Adults.Risk management and healthcare policy · 2024Article
- Observation of the effect of posterior scleral reinforcement combined with orthokeratology and 0.01% atropine in the treatment of congenital myopia: a case report.BMC ophthalmology · 2023Article
- Effects of posterior staphyloma on choroidal structure in myopic adults: a retrospective study.BMC ophthalmology · 2023Article
- Prevalence and associated health and lifestyle factors of myopic maculopathy in northern China: the Kailuan eye study.BMC ophthalmology · 2023Article
- Relationship Between Paravascular Abnormalities and Choroidal Thickness in Young Highly Myopic Adults.Translational vision science & technology · 2022Article
- Complications of high myopia: An update from clinical manifestations to underlying mechanisms.Advances in ophthalmology practice and researchReview
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11 authors at 2 institutions in 1 country.
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Abstract
purposeTo investigate the percentages and risk factors for visual impairment (VI) across age groups in a highly myopic cohort with a wide range of age (18-93 years).
methodsA total of 2099 eyes (1220 participants) were enrolled. All participants underwent detailed ocular examinations. Myopic maculopathy (MM) was assessed as myopic atrophy maculopathy (MAM), myopic traction maculopathy (MTM) or myopic neovascular maculopathy (MNM) based on the ATN system.
resultsMost participants younger than 50 years had normal vision, while the cumulative risk of VI and blindness gradually increased after 50-59 years. The percentage of each type of MM increased nonlinearly with ageing (all p < 0.001), with an accelerated period of increase after 45 years for MAM, and after 50 years for MTM and MNM. Axial length (AL) ≥30 mm was the only associated factor for mild VI or worse in participants aged 18-39 years (p < 0.001). Older age, AL ≥30 mm and the presence of MAM were predictors for mild VI or worse in the group aged 40-49 years (all p < 0.05). In participants aged ≥50 years, older age, female sex, longer AL and increased severity of MM were risk factors for VI and blindness (all p < 0.05).
conclusionThe percentages of MM and related VI increased nonlinearly with older age, with a turning point at 45 years for MAM, preceding that of MTM, MNM and VI by 5 years, warranting future longitudinal studies to confirm. Different age groups presented different risk factors for VI. Timely screening should be in place for middle-aged high myopes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.