Evidence map›Paper›PMID 34605500›Full record

ReviewDalton transactions (Cambridge, England : 2003)2021

Enzyme-activated probes in optical imaging: a focus on atherosclerosis.

Edward R H Walter, Saul M Cooper, Joseph J Boyle, Nicholas J Long

Open access · hybridAbstract readReview
In one paragraph

Review in Dalton transactions (Cambridge, England : 2003), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Edward R H WalterDepartment of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, Wood Lane, London W12 0BZ, UK. n.long@imperial.ac.uk.ORCID http://orcid.org/0000-0002-1396-3928
Saul M CooperDepartment of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, Wood Lane, London W12 0BZ, UK. n.long@imperial.ac.uk.ORCID http://orcid.org/0000-0003-0043-0249
Joseph J BoyleNational Heart and Lung Institute, Imperial College London, London, W12 0NN, UK.
Nicholas J LongDepartment of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, Wood Lane, London W12 0BZ, UK. n.long@imperial.ac.uk.ORCID http://orcid.org/0000-0002-8298-938X
Imperial College London · GB

Funding

British Heart Foundation FS/13/12/30037British Heart Foundation PG/17/71/33242British Heart Foundation PG/21/10422Medical Research Council MC_PC_19040
6 · The paper itself

Abstract

Enzyme-activated probes enable complex biological processes to be studied in real-time. A wide range of enzymes are modulated in diseases, including cancer, inflammatory diseases and cardiovascular disease, and have the potential to act as vital diagnostic and prognostic biomarkers to monitor and report on disease progression. In this perspective article, we discuss suitable design characteristics of enzyme-activated fluorescent probes for

Indexed as

AtherosclerosisFluorescent DyesOptical ImagingAnimalsCathepsinsHeme Oxygenase-1HumansPeroxidaseThrombinCathepsinsFluorescent DyesHeme Oxygenase-1PeroxidaseThrombin

Identifiers

PMID34605500
PMCPMC8546924
OpenAlexW3202766188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.