Evidence map›Paper›PMID 34605220›Full record

ArticlePhysiological reports2021

Sex and race contribute to variation in mitochondrial function and insulin sensitivity.

Gordon Fisher, Jeannie Tay, Jonathan L Warren, W Timothy Garvey, Ceren Yarar-Fisher, Barbara A Gower

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Gordon FisherDepartments of Human Studies, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0002-9191-3774
Jeannie TayDepartments of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Jonathan L WarrenDepartments of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama, USA.
W Timothy GarveyDepartments of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Ceren Yarar-FisherDepartments of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Barbara A GowerDepartments of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama, USA.
University of Alabama at Birmingham · USAgency for Science, Technology and Research · SG

Funding

Why is the prevalence of obesity so high in U.S. Southern States? Regional predictors of BMI and obesity treatment response.P30DK056336 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER · 2000 to 2026
$31.9M
University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Kirk Michael Habegger · 2013 to 2026
$19.5M
Interdisciplinary Training in Pathobiology and Rehabilitation Medicine.T32HD071866 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI JAMES RIMMER, Anna E. Thalacker-Mercer · 2012 to 2026
$4.8M
Race - adiposity interactions regulate mechanisms determining insulin sensitivityR01DK096388 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GOWER, BARBARA A · 2013 to 2017
$2.6M
NICHD NIH HHS T32 HD071866NIDDK NIH HHS P30 DK056336NIDDK NIH HHS P30 DK079626NIDDK NIH HHS R01 DK096388
6 · The paper itself

Abstract

objectiveInsulin sensitivity is lower in African American (AA) versus Caucasian American (CA). We tested the hypothesis that lower insulin sensitivity in AA could be explained by mitochondrial respiratory rates, coupling efficiency, myofiber composition, or H

methodsAA and CA men and women, 19-45 years, BMI 17-43 kg m

resultsSI

conclusionNeither mitochondrial respiratory rates, coupling efficiency, myofiber composition, nor mitochondrial reactive oxygen species production explained lower SI

Indexed as

AdultCross-Sectional StudiesFemaleGlucose Clamp TechniqueHumansHypoglycemic AgentsInsulinInsulin ResistanceMaleMiddle AgedMitochondria, MuscleMuscle, SkeletalReactive Oxygen SpeciesSex FactorsYoung AdultHypoglycemic AgentsInsulinReactive Oxygen Speciesinsulin sensitivitymitochondrial functionracereactive oxygen speciessex

Identifiers

PMID34605220
PMCPMC8488557
OpenAlexW3203153817

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.