Evidence map›Paper›PMID 34605181›Full record

Observational studyInfluenza and other respiratory viruses2022

Transmission of SARS-CoV-2 during a 2-h domestic flight to Okinawa, Japan, March 2020.

Takao Toyokawa, Tomoe Shimada, Takahiro Hayamizu, Tsuyoshi Sekizuka, Yuji Zukeyama, Miyako Yasuda, Yuko Nakamura, Sho Okano, Jun Kudaka, Tetsuya Kakita and 2 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Influenza and other respiratory viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 5 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 5 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Estimation of air change rate by COEnvironmental and occupational health practice · 2023
    Article
  13. Article
  14. Article
  15. Covid-19 infection risk on US domestic airlines.Health care management science · 2022
    Article
  16. Article
  17. The COVID-19 pandemic: Virus transmission and risk assessment.Current opinion in environmental science & health · 2022
    Review
  18. Review
  19. SARS-CoV-2 Transmission and Prevention in the Era of the Delta Variant.Infectious disease clinics of North America · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Takao ToyokawaCOVID-19 Response Team, Naha City Public Health Center, Naha-shi, Okinawa, Japan.ORCID 0000-0003-3872-6977
Tomoe ShimadaInfectious Disease Surveillance Center, National Institute of Infectious Diseases (NIID), Shinjuku-ku, Tokyo, Japan.
Takahiro HayamizuCOVID-19 Response Team, Naha City Public Health Center, Naha-shi, Okinawa, Japan.
Tsuyoshi SekizukaPathogen Genomics Center, National Institute of Infectious Diseases (NIID), Shinjuku-ku, Tokyo, Japan.
Yuji ZukeyamaCOVID-19 Response Team, Naha City Public Health Center, Naha-shi, Okinawa, Japan.
Miyako YasudaCOVID-19 Response Team, Naha City Public Health Center, Naha-shi, Okinawa, Japan.
Yuko NakamuraCOVID-19 Response Team, Naha City Public Health Center, Naha-shi, Okinawa, Japan.
Sho OkanoRegional Health Division, Department of Public Health and Medical Care, Okinawa Prefectural Government, Naha-shi, Okinawa, Japan.
Jun KudakaRegional Health Division, Department of Public Health and Medical Care, Okinawa Prefectural Government, Naha-shi, Okinawa, Japan.
Tetsuya KakitaOkinawa Prefectural Institute of Health and Environment, Uruma-shi, Okinawa, Japan.ORCID 0000-0002-8991-7397
Makoto KurodaPathogen Genomics Center, National Institute of Infectious Diseases (NIID), Shinjuku-ku, Tokyo, Japan.
Tadashi NakasoneCOVID-19 Response Team, Naha City Public Health Center, Naha-shi, Okinawa, Japan.
Naha City Hospital · JPNational Institute of Infectious Diseases · JPOkinawa Prefecture · JPOkinawa Prefectural Institute of Health and Environment · JP

Funding

Japan Agency for Medical Research and Development JP19fk0108104Japan Agency for Medical Research and Development JP20fk0108063Japan Agency for Medical Research and Development JP20fk0108103Ministry of Health, Labour and Welfare of Japan
6 · The paper itself

Abstract

backgroundCoronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus (SARS-CoV-2), has rapidly spread globally. Potentially infected individuals travel on commercial aircraft. Thus, this study aimed to investigate and test the association between the use of face masks, physical distance, and COVID-19 among passengers and flight attendants exposed to a COVID-19 passenger in a domestic flight.

methodsThis observational study investigated passengers and flight attendants exposed to COVID-19 on March 23, 2020, on board a flight to Naha City, Japan. Secondary attack rates were calculated. Whole-genome sequencing of SARS-CoV-2 was used to identify the infectious linkage between confirmed cases in this clustering. The association between confirmed COVID-19 and proximity of passengers' seats to the index case and/or the use of face masks was estimated using logistic regression.

resultsFourteen confirmed and six probable cases were identified among passengers and flight attendants. The secondary attack rate was 9.7%. Twelve of 14 SARS-CoV-2 genome sequences in confirmed cases were identical to that of the index case or showed only one nucleotide mutation. Risk factors for infection included not using a face mask (adjusted odds ratio [aOR]: 7.29, 95% confidence interval [95% CI]: 1.86-28.6), partial face mask use (aOR: 3.0, 95% CI: 0.83-10.8), and being seated within two rows from the index patient (aOR: 7.47, 95% CI: 2.06-27.2).

conclusionSARS-CoV-2 was transmitted on the airplane. Nonuse of face masks was identified as an independent risk factor for contracting COVID-19 on the airplane.

Indexed as

Air TravelCOVID-19HumansJapanMasksSARS-CoV-2cohort studiesCOVID-19disease outbreaksmolecular epidemiologySARS-CoV-2travel-related illness

Identifiers

PMID34605181
PMCPMC8652895
OpenAlexW3202801737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.