Evidence map›Paper›PMID 34605117›Full record

SynthesisInternational journal of clinical practice2021

Bowel ischemia in COVID-19: A systematic review.

Suyog Patel, Charmy Parikh, Deepak Verma, Ramaswamy Sundararajan, Upasana Agrawal, Niharika Bheemisetty, Radhika Akku, Diana Sánchez-Velazco, Madeeha Subhan Waleed

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in International journal of clinical practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Bowel ischemia in COVID-19: A systematic review.International journal of clinical practice · 2021
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Diarrhea and Coronavirus Disease 2019 Infection.Gastroenterology clinics of North America · 2023
    Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Acute Mesenteric Ischemia in COVID-19 Patients.Journal of clinical medicine · 2021
    Review
  18. Acute abdomen: postmortem analysis of 31 cases in the Emergency Department - a monocentric retrospective study.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 9 institutions in 4 countries.

Suyog PatelDepartment of Medicine, B.J. Medical College, Ahmedabad, India.
Charmy ParikhPramukh Swami Medical College, Anand, India.
Deepak VermaDepartment of Medicine, Janaki Medical College, Janakpur, Nepal.
Ramaswamy SundararajanJSS Medical College, Mysore, India (JSS Academy of Higher Education and Research), Mysore, India.
Upasana AgrawalKasturba Medical College, Manipal, India.
Niharika BheemisettyDepartment of Pediatrics, KS Multi-Speciality Hospital, Secunderabad, India.
Radhika AkkuMediciti Institute of Medical Sciences, Hyderabad, India.
Diana Sánchez-VelazcoDepartment of Medicine, Cayetano Heredia Peruvian University, Lima, Peru.
Madeeha Subhan WaleedDepartment of Medicine, Ayub Medical College, Abbottabad, Pakistan.
Ayub Medical College · PKB.J. Medical College · INJSS Academy of Higher Education and Research · INKasturba Medical College, Manipal · INMediciti Institute of Medical Sciences · INNepal Medical College Teaching Hospital · NPPramukhswami Medical College · INTamil Nadu Government Multi Super Speciality Hospital · INUniversidad Peruana Cayetano Heredia · PE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGastrointestinal complications of COVID-19 have been reported over the last year. One such manifestation is bowel ischaemia. This study thus aims to provide a more holistic review of our current understanding of COVID-19-induced bowel ischaemia. METHOD AND

resultsA meticulous search was performed using different keywords in PubMed and Google Scholar. Fifty-two articles were included in our study after applying inclusion and exclusion criteria and performing the qualitative assessment of the studies. A total of 25 702 patients were included in our study after the completion of the qualitative assessment. DISCUSSION: The common symptoms of GIT in COVID-19 patients are as diarrhoea, vomiting, nausea and abdominal pain. The mechanism of bowel ischaemia is associated with the formation of emboli which is related to COVID-19's high affinity for angiotensin-converting enzyme-2 on enterocytes, affecting the superior mesenteric vessels. Clinically, patients present with abdominal pain and vomiting. CT angiography of the abdomen and pelvis showed acute intestinal ischaemia (mesenteric). Management is usually initiated with gastric decompression, fluid resuscitation, and haemodynamic support. Surgical intervention is also sought.

conclusionIntestinal ischaemia presenting in patients with COVID-19 has to be considered when symptoms of severe abdominal pain are present. More research and guidelines are required to triage patients with COVID-19 to suspect intestinal ischaemia and to help in diagnosis and management.

Indexed as

COVID-19Gastrointestinal DiseasesMesenteric IschemiaHumansIschemiaSARS-CoV-2

Identifiers

PMID34605117
PMCPMC8646310
OpenAlexW3201715993

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.