ArticleJournal of clinical periodontology2021
Associations of periodontal disease and tooth loss with all-cause and cause-specific mortality in the Sister Study.
Article in Journal of clinical periodontology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Examining the link between tooth loss and multiple health outcomes: a comprehensive synthesis of evidence from meta-analyses.Frontiers in public health · 2026Pooled it
- Anti-Inflammatory Effects on Periodontal Tissue and Antibacterial Effects on Oral Bacteria of Chlorogenic Acid.Dentistry journal · 2026Article
- Graph neural network-based prediction of all-cause and cardiovascular mortality using periodontal site-level data from National Health and Nutrition Examination Survey (NHANES).Journal of dental sciences · 2026Article
- Racial/Ethnic Differences in the Joint Effect of Edentulism and Diabetes on All-Cause Mortality Risks: A 12-Year Prospective Cohort Analysis.Journal of public health dentistry · 2025Article
- Chewing difficulty, swallowing problems, xerostomia and cause-specific mortality among older adults: A 7-year follow-up JAGES cohort study.Geriatrics & gerontology international · 2025Article
- Contribution of dental prostheses on the association between dental visits and self- reported chewing ability among older Japanese adults: a cross-sectional study.BMC oral health · 2025Article
- Association between the number of teeth and all-cause mortality rate in the MASHAD Cohort Study.Journal of dental research, dental clinics, dental prospects · 2025Article
- Association of oral health with all-cause and cause-specific mortality in older Chinese adults: A 14-year follow-up of the Guangzhou Biobank Cohort study.Journal of global health · 2024Article
- Zirconia Dental Implants Surface Electric Stimulation Impact onInternational journal of molecular sciences · 2024Article
- Dental health and lung cancer risk in the Golestan Cohort Study.BMC cancer · 2024Article
- Co-Payments and Inequality in Gingival Bleeding and Dental Visits.International dental journal · 2023Article
- The association between poor oral health and risk of breast cancer in the UK Biobank.Cancer causes & control : CCC · 2023Article
- Tooth loss, denture use, and all-cause and cause-specific mortality in older adults: a community cohort study.Frontiers in public health · 2023Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
aimStudies have found that periodontal disease and tooth loss are associated with increased mortality; however, associations with cause-specific mortality and all-cause mortality within specific subgroups have not been thoroughly investigated. MATERIALS AND
methodsWe examined the association of self-reported periodontal disease and disease/decay-related tooth loss with subsequent all-cause and cause-specific mortality in the Sister Study, a prospective cohort study of 50,884 women aged 35-74 years at baseline, whose sister was diagnosed with breast cancer. Hazard ratios (HRs) and 95% confidence intervals (95% CIs) for the associations were calculated with adjustment for relevant confounders.
resultsWith a mean follow-up of 10.9 years (range 0.1-14.3), 2058 women died. Participants with periodontal disease had a slightly higher rate of all-cause mortality (HR = 1.08, 95% CI 0.98-1.19), while participants with tooth loss had an increased rate of all-cause mortality (HR = 1.15, 95% CI 1.05-1.26). For cause-specific mortality, women with tooth loss had increased rates of death from circulatory system diseases, respiratory system diseases, and endocrine/metabolic diseases. Results varied in stratified models, but no heterogeneity across strata was found.
conclusionsIn this large prospective study, periodontal disease and tooth loss were associated with all-cause and certain specific cause-specific mortality outcomes.
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