ArticleInternational journal of cancer2022
The unfavorable effects of COVID-19 on Dutch advanced melanoma care.
Article in International journal of cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Physical and mental health outcomes of COVID-19 induced delay in oncological care: A systematic review.Frontiers in oncology · 2023Pooled it
- The Epidemiology of Malignant Melanoma during the First Two Years of the COVID-19 Pandemic: A Systematic Review.International journal of environmental research and public health · 2022Pooled it
- COVID-19's Shadow: The Effect of COVID-19 on Cytopathology Specimens Received at an Academic Laboratory in Central South Africa.Cytopathology : official journal of the British Society for Clinical Cytology · 2026Article
- Effect of the COVID-19 pandemic and lockdown on cancer stage distribution and time to treatment initiation using cancer registry data of the Swiss cantons of Zurich and Zug from 2018 to 2021.Journal of cancer research and clinical oncology · 2025Article
- The Impact of the COVID-19 Pandemic on Melanoma Diagnosis: A Single-Center Study.Diagnostics (Basel, Switzerland) · 2024Article
- Improving survival in advanced melanoma patients: a trend analysis from 2013 to 2021.EClinicalMedicine · 2024Article
- Impact of the COVID-19 pandemic on the in-hospital diagnostic pathway of breast and colorectal cancer in the Netherlands: A population-based study.Cancer medicine · 2024Article
- The effects of the COVID-19 pandemic on the diagnosis and prognosis of melanoma 2 years after the pandemic in two Romanian counties.Frontiers in medicine · 2024Article
- The impact of the COVID-19 pandemic on the diagnosis and treatment of skin cancers, a mini review.Cancer reports (Hoboken, N.J.) · 2023Review
- The Impact of the COVID Pandemic on the Incidence of Presentations with Cancer-Related Symptoms in Primary Care.Cancers · 2022Article
- Limited impact of COVID-19-related diagnostic delay on cutaneous melanoma and squamous cell carcinoma tumour characteristics: a nationwide pathology registry analysis.The British journal of dermatology · 2022Article
- Impact of the COVID-19 Pandemic on the Diagnosis and Prognosis of Melanoma.Journal of clinical medicine · 2022Article
- Cancer diagnosis in Catalonia (Spain) after two years of COVID-19 pandemic: an incomplete recovery.ESMO open · 2022Article
- Article
- The unfavorable effects of COVID-19 on Dutch advanced melanoma care.International journal of cancer · 2022Article
- Fear of Progression, Anxiety, and Depression in Patients With Advanced Melanoma in the COVID-19 and Post-COVID-19 Era.Frontiers in psychiatry · 2022Article
Corrections and comments
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Authors and funding
22 authors at 15 institutions in 1 country.
Funding
Abstract
The COVID-19 pandemic had a severe impact on medical care. Our study aims to investigate the impact of COVID-19 on advanced melanoma care in the Netherlands. We selected patients diagnosed with irresectable stage IIIc and IV melanoma during the first and second COVID-19 wave and compared them with patients diagnosed within the same time frame in 2018 and 2019. Patients were divided into three geographical regions. We investigated baseline characteristics, time from diagnosis until start of systemic therapy and postponement of anti-PD-1 courses. During both waves, fewer patients were diagnosed compared to the control groups. During the first wave, time between diagnosis and start of treatment was significantly longer in the southern region compared to other regions (33 vs 9 and 15 days, P-value <.05). Anti-PD-1 courses were postponed in 20.0% vs 3.0% of patients in the first wave compared to the control period. Significantly more patients had courses postponed in the south during the first wave compared to other regions (34.8% vs 11.5% vs 22.3%, P-value <.001). Significantly more patients diagnosed during the second wave had brain metastases and worse performance status compared to the control period. In conclusion, advanced melanoma care in the Netherlands was severely affected by the COVID-19 pandemic. In the south, the start of systemic treatment for advanced melanoma was more often delayed, and treatment courses were more frequently postponed. During the second wave, patients were diagnosed with poorer patient and tumor characteristics. Longer follow-up is needed to establish the impact on patient outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.