Evidence map›Paper›PMID 34604844›Full record

ArticleJACS Au2021

Targeted Antibacterial Strategy Based on Reactive Oxygen Species Generated from Dioxygen Reduction Using an Organoruthenium Complex.

Cheng Weng, Linghui Shen, Jin Wei Teo, Zhi Chiaw Lim, Boon Shing Loh, Wee Han Ang

Open access · goldAbstract read
In one paragraph

Article in JACS Au, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The Antimicrobial Properties of PdChembiochem : a European journal of chemical biology · 2023
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Cheng WengDepartment of Chemistry, National University of Singapore, 4 Science Drive 2, Singapore 117544, Singapore.
Linghui ShenDepartment of Chemistry, National University of Singapore, 4 Science Drive 2, Singapore 117544, Singapore.
Jin Wei TeoDepartment of Chemistry, National University of Singapore, 4 Science Drive 2, Singapore 117544, Singapore.
Zhi Chiaw LimDepartment of Chemistry, National University of Singapore, 4 Science Drive 2, Singapore 117544, Singapore.ORCID https://orcid.org/0000-0001-7398-8513
Boon Shing LohDepartment of Chemistry, National University of Singapore, 4 Science Drive 2, Singapore 117544, Singapore.
Wee Han AngDepartment of Chemistry, National University of Singapore, 4 Science Drive 2, Singapore 117544, Singapore.ORCID https://orcid.org/0000-0003-2027-356X
National University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pathogenic microorganisms pose a serious threat to global public health due to their persistent adaptation and growing resistance to antibiotics. Alternative therapeutic strategies are required to address this growing threat. Bactericidal antibiotics that are routinely prescribed to treat infections rely on hydroxyl radical formation for their therapeutic efficacies. We developed a redox approach to target bacteria using organotransition metal complexes to mediate the reduction of cellular O

Identifiers

PMID34604844
PMCPMC8479771
OpenAlexW3197818286

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.