Evidence map›Paper›PMID 34604747›Full record

ReviewJAC-antimicrobial resistance2021

Navigating sociocultural disparities in relation to infection and antibiotic resistance-the need for an intersectional approach.

Esmita Charani, Marc Mendelson, Diane Ashiru-Oredope, Eleanor Hutchinson, Manmeet Kaur, Martin McKee, Mirfin Mpundu, James R Price, Nusrat Shafiq, Alison Holmes

Open access · goldAbstract readReview
In one paragraph

Review in JAC-antimicrobial resistance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.

  1. Pooled it
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  3. Unveiling the antibiotic resistance pattern inWorld journal of experimental medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 4 countries.

Esmita CharaniNational Institute for Health Research Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Imperial College London, London, UK.ORCID https://orcid.org/0000-0002-5938-1202
Marc MendelsonDivision of Infectious Diseases and HIV Medicine, Department of Medicine, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa.
Diane Ashiru-OredopePublic Health England, London, UK.ORCID https://orcid.org/0000-0001-9579-2028
Eleanor HutchinsonLondon School of Hygiene and Tropical Medicine, London, UK.
Manmeet KaurPostgraduate Institute of Medical Education and Research, Chandigarh, India.
Martin McKeeLondon School of Hygiene and Tropical Medicine, London, UK.ORCID https://orcid.org/0000-0002-0121-9683
Mirfin MpunduInternational Centre for Antimicrobial Resistance Solutions, Lusaka, Zambia.
James R PriceImperial College Healthcare NHS Trust, Department of Infectious Diseases, London, UK.
Nusrat ShafiqPostgraduate Institute of Medical Education and Research, Chandigarh, India.ORCID https://orcid.org/0000-0001-7053-003X
Alison HolmesNational Institute for Health Research Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Imperial College London, London, UK.
London School of Hygiene & Tropical Medicine · GBPost Graduate Institute of Medical Education and Research · INUniversity of Cape Town · ZACentre for Infectious Disease Research in Zambia · ZMImperial College Healthcare NHS Trust · GBNational Institute for Health Research · GBPublic Health England · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the key drivers of antibiotic resistance (ABR) and drug-resistant bacterial infections is the misuse and overuse of antibiotics in human populations. Infection management and antibiotic decision-making are multifactorial, complex processes influenced by context and involving many actors. Social constructs including race, ethnicity, gender identity and cultural and religious practices as well as migration status and geography influence health. Infection and ABR are also affected by these external drivers in individuals and populations leading to stratified health outcomes. These drivers compromise the capacity and resources of healthcare services already over-burdened with drug-resistant infections. In this review we consider the current evidence and call for a need to broaden the study of culture and power dynamics in healthcare through investigation of relative power, hierarchies and sociocultural constructs including structures, race, caste, social class and gender identity as predictors of health-providing and health-seeking behaviours. This approach will facilitate a more sustainable means of addressing the threat of ABR and identify vulnerable groups ensuring greater inclusivity in decision-making. At an individual level, investigating how social constructs and gender hierarchies impact clinical team interactions, communication and decision-making in infection management and the role of the patient and carers will support better engagement to optimize behaviours. How people of different race, class and gender identity seek, experience and provide healthcare for bacterial infections and use antibiotics needs to be better understood in order to facilitate inclusivity of marginalized groups in decision-making and policy.

Identifiers

PMID34604747
PMCPMC8485076
OpenAlexW3202058860

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.