Evidence map›Paper›PMID 34604682›Full record

ArticleACS omega2021

Synthesis of 12β-Methyl-18-

Andreas Luxenburger, Lawrence D Harris, Elizabeth M Ure, Roselis A Landaeta Aponte, Anthony D Woolhouse, Scott A Cameron, Chris D Ling, Ross O Piltz, Andrew R Lewis, Graeme J Gainsford and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. 3α,7-Dihydroxy-14(13→12)Biomolecules · 2022
    Article
  2. Synthesis of Novel C/D Ring Modified Bile Acids.Molecules (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Andreas LuxenburgerFerrier Research Institute, Victoria University of Wellington, 69 Gracefield Rd, Lower Hutt 5040, New Zealand.ORCID https://orcid.org/0000-0002-7574-8027
Lawrence D HarrisFerrier Research Institute, Victoria University of Wellington, 69 Gracefield Rd, Lower Hutt 5040, New Zealand.ORCID https://orcid.org/0000-0002-4214-1018
Elizabeth M UreFerrier Research Institute, Victoria University of Wellington, 69 Gracefield Rd, Lower Hutt 5040, New Zealand.
Roselis A Landaeta AponteFerrier Research Institute, Victoria University of Wellington, 69 Gracefield Rd, Lower Hutt 5040, New Zealand.
Anthony D WoolhouseFerrier Research Institute, Victoria University of Wellington, 69 Gracefield Rd, Lower Hutt 5040, New Zealand.
Scott A CameronFerrier Research Institute, Victoria University of Wellington, 69 Gracefield Rd, Lower Hutt 5040, New Zealand.ORCID https://orcid.org/0000-0003-2669-8622
Chris D LingSchool of Chemistry, The University of Sydney, Sydney, New South Wales 2006, Australia.ORCID https://orcid.org/0000-0003-2205-3106
Ross O PiltzAustralian Centre for Neutron Scattering, New Illawarra Rd, Lucas Heights, Sydney, New South Wales 2234, Australia.ORCID https://orcid.org/0000-0003-0867-3712
Andrew R LewisCallaghan Innovation, P.O. Box 31 310, Lower Hutt 5040, New Zealand.
Graeme J GainsfordFerrier Research Institute, Victoria University of Wellington, 69 Gracefield Rd, Lower Hutt 5040, New Zealand.
Alex Weymouth-WilsonNew Zealand Pharmaceuticals Ltd, 68 Weld Street, RD2, Palmerston North 4472, New Zealand.
Richard H FurneauxFerrier Research Institute, Victoria University of Wellington, 69 Gracefield Rd, Lower Hutt 5040, New Zealand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Decoupling the roles of the farnesoid X nuclear receptor and Takeda G-protein-coupled bile acid receptor 5 is essential for the development of novel bile acid therapeutics targeting metabolic and neurodegenerative diseases. Herein, we describe the synthesis of 12β-methyl-18-

Identifiers

PMID34604682
PMCPMC8482778

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.