ArticleACS omega2021
Synthesis, Characterization, Immune Regulation, and Antioxidative Assessment of Yeast-Derived Selenium Nanoparticles in Cyclophosphamide-Induced Rats.
Article in ACS omega, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 60 citations in OpenAlex.
- Amorphous selenium nanoparticles: synthesis strategies and multifunctional applications.RSC advances · 2026Review
- Selenized neural stem cell-derived exosomes: A neotype therapeutic agent for traumatic injuries of the central nervous system.Cell reports. Medicine · 2025Article
- Transforming bone cancer treatment: a comprehensive review of green-synthesized metal nanoparticles.Cancer cell international · 2025Review
- A nano-bioengineered cobalt oxide biostimulant mediated regulation of physiological, biochemical, and antioxidant mechanisms in Zea mays.Scientific reports · 2025Article
- Analysis of Fluorescent Carbon Nanodots Synthesized from Spices Through Thermal Processes Treatment.Nanomaterials (Basel, Switzerland) · 2025Article
- Physio-biochemical insights into Arsenic stress mitigation regulated by Selenium nanoparticles in Gossypium hirsutum L.BMC plant biology · 2025Article
- Biogenic zinc oxide nanoregulator determines the quantitative analysis of morpho-anatomical and antioxidant capacity inFood science & nutrition · 2024Article
- Green synthesis, characterization and functional validation of bio-transformed selenium nanoparticles.Biochemistry and biophysics reports · 2024Article
- Zinc oxide nano-fertilizer differentially effect on morphological and physiological identity of redox-enzymes and biochemical attributes in wheat (Triticum aestivum L.).Scientific reports · 2024Article
- Effects of yeast peptides on the growth, antioxidant and anti-inflammatory capacities, immune function, and diarrhea status of suckling calves.Frontiers in veterinary science · 2024Article
- Enhancing Health Benefits through Chlorophylls and Chlorophyll-Rich Agro-Food: A Comprehensive Review.Molecules (Basel, Switzerland) · 2023Review
- A Comparative Study of the Synthesis and Characterization of Biogenic Selenium Nanoparticles by Two Contrasting Endophytic Selenobacteria.Microorganisms · 2023Article
- Article
- Biological Selenite Reduction, Characterization and Bioactivities of Selenium Nanoparticles Biosynthesised byMolecules (Basel, Switzerland) · 2023Article
- Review
- Bioinspired Cobalt Oxide Nanoball Synthesis, Characterization, and Their Potential as Metal Stress Absorbants.ACS omega · 2023Article
- Plant and Microbial Approaches as Green Methods for the Synthesis of Nanomaterials: Synthesis, Applications, and Future Perspectives.Molecules (Basel, Switzerland) · 2023Review
- Selenium-Containing Agents Acting on Cancer-A New Hope?Pharmaceutics · 2022Review
- Article
- Crest to Trough Cellular Drifting of Green-Synthesized Zinc Oxide and Silver Nanoparticles.ACS omega · 2022Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This article introduces an environmentally friendly and more economical method for preparing red selenium nanoparticles (Se-NPs) with high stability, good biocompatibility, and narrow size using yeast as a bio-reducing agent with high antioxidant, immune regulation, and low toxicity than inorganic and organic Se. The yeast-derived Se-NPs were characterized by scanning electron microscopy, transmission electron microscopy, energy dispersive spectroscopy, Fourier transform infrared spectroscopy, X-ray diffraction, and X-ray photoelectron spectroscopy. The results revealed spherical-shaped particles of Se-NPs with an average diameter of 71.14 ± 18.17 nm, an amorphous structure, and surface enhancement with an organic shell layer, that provide precise geometry and stability in the formation of bio-inert gray or black Se-NPs instead of red Se-NPs. Furthermore, the addition of 0.3-0.8 mg/kg Se-NPs in the feed significantly improved the health of mice. As Se-NPs stimulated the oxidative state of mice, it significantly increased the level of GSH-Px, SOD, and AOC, and decreased the level of MDA. The yeast-derived Se-NPs alleviated the immunosuppression induced by cyclophosphamide, whereas protected the liver, spleen, and kidney of mice, stimulated the humoral immune potential of the mice, and significantly increased the levels of I g M, IgA, and I g G. These results indicated that the yeast-derived Se-NPs, as a trace element feed additive, increased the defense of the animal against oxidative stress and infectious diseases and therefore Se-NPs can be used as a potential antibiotic substitute for animal husbandry.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.