Evidence map›Paper›PMID 34604599›Full record

ArticleJournal of preventive medicine and hygiene2021

Edoardo Maragliano (1849-1940) and the immunogenicity of the tubercle bacillus: the pathway of a great italian physician.

Mariano Martini, Niccolò Riccardi, Edoardo Maragliano, Francesco Brigo

Open access · greenAbstract readBiographyHistorical Article
In one paragraph

Article in Journal of preventive medicine and hygiene, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 81% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 0 citations in OpenAlex.

  1. Historical and Social Considerations upon Tuberculosis.Journal of preventive medicine and hygiene · 2025
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  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mariano MartiniDepartment of Health Sciences, University of Genoa, Genoa, Italy.
Niccolò RiccardiDepartment of Infectious - Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar, Verona, Italy.
Edoardo MaraglianoIndipendent Scholar, Genoa, Italy.
Francesco BrigoDepartment of Neurology, Hospital of Merano (SABES-ASDAA), Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Edoardo Maragliano (1849-1940) was an Italian physician; he played a central role in medicine's "renaissance" in Italy and Europe. After beginning his academic career as a professor of pathology, he became full professor of internal medicine in 1881. While he studied all fields of internal medicine, his research focused mainly on tuberculosis. Thanks to his experiments in the medical clinic, Maragliano announced the possibility of immunization against Mycobacterium tuberculosis. Although criticized for using an inactivated vaccine, Maragliano continued to advocate vaccination with any type of vaccine. Maragliano keenly contributed to the still ongoing process of understanding the difficult interaction between Mycobacterium tuberculosis and the infected host.

Indexed as

BacillusImmunogenicity, VaccineTuberculosisHistory, 19th CenturyHumansItalyMycobacterium tuberculosisPhysiciansTuberculosis VaccinesTuberculosis VaccinesEdoardo MaraglianoHistory of tuberculosisImmunogenicityTuberculosis

Identifiers

PMID34604599
PMCPMC8451332
OpenAlexW3204848602

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.