Evidence map›Paper›PMID 34604437›Full record

ArticleACG case reports journal2020

Alcoholic Hepatitis and COVID-19: The Question of Steroids.

Sara Zelman, Erik Holzwanger, Raza Malik, Aaron Dickstein

Open access · diamondAbstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Covid-19 and alcohol associated liver disease.Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver · 2022
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sara ZelmanDepartment of Gastroenterology and Hepatology, Tufts Medical Center, Boston, MA.
Erik HolzwangerDepartment of Gastroenterology and Hepatology, Tufts Medical Center, Boston, MA.
Raza MalikDepartment of Gastroenterology and Hepatology, Tufts Medical Center, Boston, MA.
Aaron DicksteinDepartment of Gastroenterology and Hepatology, Tufts Medical Center, Boston, MA.
Tufts Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus 2/novel coronavirus-19 (COVID-19) has rapidly become a global pandemic since the first cases from Wuhan, China, were reported in December 2019. The pandemic has made it more challenging to treat various gastrointestinal disorders, including acute alcoholic hepatitis (AH). One of the mainstays of treatment for severe AH involves corticosteroids (mainly prednisolone). A concern when treating with prednisolone is the worsening of underlying infection. There may be an additional risk in treating COVID-19-infected patients. We present a case of a patient with severe acute AH and concomitant COVID-19 infection who did well with corticosteroid therapy without evidence for worsening infection.

Identifiers

PMID34604437
PMCPMC8483816
OpenAlexW3112209085

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.