Evidence map›Paper›PMID 34604239›Full record

ArticleFrontiers in cell and developmental biology2021

miR-29b-3p Increases Radiosensitivity in Stemness Cancer Cells

Dong Pan, Yarong Du, Rong Li, Aihua Shen, Xiaodong Liu, Chuanyuan Li, Burong Hu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

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  6. Non-coding RNAs modulation in breast cancer radioresponse: mechanisms and therapeutic implications.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Dong PanDepartment of Radiation Medicine, School of Public Health and Management, Wenzhou Medical University, Wenzhou, China.
Yarong DuKey Laboratory of Heavy Ion Radiation Biology and Medicine of Chinese Academy of Sciences, Key Laboratory of Space Radiobiology of Gansu Province, Institute of Modern Physics, Chinese Academy of Sciences (CAS), Lanzhou, China.
Rong LiDepartment of Radiation Medicine, School of Public Health and Management, Wenzhou Medical University, Wenzhou, China.
Aihua ShenDepartment of Radiation Medicine, School of Public Health and Management, Wenzhou Medical University, Wenzhou, China.
Xiaodong LiuDepartment of Radiation Medicine, School of Public Health and Management, Wenzhou Medical University, Wenzhou, China.
Chuanyuan LiDepartment of Dermatology, Duke University Medical Center, Durham, NC, United States.
Burong HuDepartment of Radiation Medicine, School of Public Health and Management, Wenzhou Medical University, Wenzhou, China.
Wenzhou Medical University · CNInstitute of Modern Physics · CNChinese Academy of Sciences · CNDuke Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radioresistance conferred by cancer stem cells (CSCs) is the principal cause of the failure of cancer radiotherapy. Eradication of CSCs is a prime therapeutic target and a requirement for effective radiotherapy. Three dimensional (3D) cell-cultured model could mimic the morphology of cells

Indexed as

miR-29b-3poncogene axisradiosensitivitystemnessthree dimensional cultured cells

Identifiers

PMID34604239
PMCPMC8481616
OpenAlexW3199954131

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.