Evidence map›Paper›PMID 34604218›Full record

ReviewFrontiers in cell and developmental biology2021

Reproductive Aging in

Andrea Scharf, Franziska Pohl, Brian M Egan, Zuzana Kocsisova, Kerry Kornfeld

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 82 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Apoptosis promotes fertility inbioRxiv : the preprint server for biology · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Probiotic Modulation in Aging: Strain-Specific Geroprotective Effects inInternational journal of molecular sciences · 2025
    Article
  16. Hyperactive 20Science advances · 2025
    Article
  17. Article
  18. NuRD chromatin remodeling is required to repair exogenous DSBs in thebioRxiv : the preprint server for biology · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Andrea ScharfDepartment of Developmental Biology, Washington University School of Medicine, St. Louis, MO, United States.
Franziska PohlDepartment of Developmental Biology, Washington University School of Medicine, St. Louis, MO, United States.
Brian M EganDepartment of Developmental Biology, Washington University School of Medicine, St. Louis, MO, United States.
Zuzana KocsisovaDepartment of Developmental Biology, Washington University School of Medicine, St. Louis, MO, United States.
Kerry KornfeldDepartment of Developmental Biology, Washington University School of Medicine, St. Louis, MO, United States.
Washington University in St. Louis · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
IDENTIFICATION OF DRUGS THAT DELAY AGINGR01AG026561 · NIA · WASHINGTON UNIVERSITY · PI KORNFELD, KERRY · 2006 to 2017
$3.3M
DISCOVER DETERMINANTS OF INDIVIDUAL LIFESPAN AND HEALTHR01AG057748 · NIA · WASHINGTON UNIVERSITY · PI KORNFELD, KERRY · 2019 to 2023
$2.1M
NIA NIH HHS R01 AG026561NIA NIH HHS R01 AG057748NIH HHS P40 OD010440
6 · The paper itself

Abstract

Aging animals display a broad range of progressive degenerative changes, and one of the most fascinating is the decline of female reproductive function. In the model organism

Indexed as

agingegg-layingevolutiongerm linematricidal hatchingmenopauseoocyte qualityreproduction

Identifiers

PMID34604218
PMCPMC8481778
OpenAlexW3200536900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.