Evidence map›Paper›PMID 34604118›Full record

ArticleFrontiers in cellular and infection microbiology2021

Rescuing eGFP-Tagged Canine Distemper Virus for 40 Serial Passages Separately in Ribavirin- and Non-Treated Cells: Comparative Analysis of Viral Mutation Profiles.

Fuxiao Liu, Ning Wang, Jiahui Lin, Qianqian Wang, Yilan Huang, Youming Zhang, Hu Shan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Fuxiao LiuCollege of Veterinary Medicine, Qingdao Agricultural University, Qingdao, China.
Ning WangCollege of Veterinary Medicine, Qingdao Agricultural University, Qingdao, China.
Jiahui LinCollege of Veterinary Medicine, Qingdao Agricultural University, Qingdao, China.
Qianqian WangCollege of Veterinary Medicine, Qingdao Agricultural University, Qingdao, China.
Yilan HuangCollege of Veterinary Medicine, Qingdao Agricultural University, Qingdao, China.
Youming ZhangState Key Laboratory of Microbial Technology, Shandong University, Qingdao, China.
Hu ShanCollege of Veterinary Medicine, Qingdao Agricultural University, Qingdao, China.
Qingdao Agricultural University · CNShandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to lacking a proofreading mechanism in their RNA-dependent RNA polymerases (RdRp), RNA viruses generally possess high mutation frequencies, making them evolve rapidly to form viral quasispecies during serial passages in cells, especially treated with mutagens, like ribavirin. Canine distemper virus (CDV) belongs to the genus

Indexed as

Distemper Virus, CanineAnimalsMutationRibavirinRNA-Dependent RNA PolymeraseSerial PassageRibavirinRNA-Dependent RNA Polymerasehigh-fidelitynext-generation sequencingquasispeciesrCDV-eGFPribavirinSNM

Identifiers

PMID34604118
PMCPMC8481889
OpenAlexW3199581659

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.