ArticleFrontiers in cellular and infection microbiology2021
Antigen Presenting Cells Link the Female Genital Tract Microbiome to Mucosal Inflammation, With Hormonal Contraception as an Additional Modulator of Inflammatory Signatures.
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Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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0cells of the map it votes in
23citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
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Who cites it
23 citing papers in PubMed, 23 citations in OpenAlex.
- Microbiota and inflammatory factor profiles in different stages of bacterial vaginosis formation and recurrence.Journal of medical microbiology · 2026Article
- Microbiota-dependent interferon-λ controls immunity of the uterus and maternal-fetal interface.Research square · 2026Article
- Differential Host Gene Expression Associated with Non-Research square · 2026Article
- Mucosal Dynamics Contributing to Innate Immune Responses to HIV in the Human Female Genital Tract.Viruses · 2026Review
- Microbiota-dependent IFN-L controls uterine and placental immunity.bioRxiv : the preprint server for biology · 2026Article
- The microbiota-host metabolic axis in cervical cancer: from homeostatic disruption to mechanisms of therapy resistance.Frontiers in cellular and infection microbiology · 2026Review
- Evaluating theFrontiers in immunology · 2026Article
- Exploring the Potential Use of Probiotics, Prebiotics, Synbiotics, and Postbiotics as Adjuvants for Modulating the Vaginal Microbiome: a Bibliometric Review.Probiotics and antimicrobial proteins · 2025Review
- Bacterial Vaginosis Is Associated With Transcriptomic Changes but Not Higher Concentrations of Cervical Leukocytes in a Study of Women at High Risk for Human Immunodeficiency Virus Acquisition.The Journal of infectious diseases · 2025Article
- Bacterial vaginosis associates with dysfunctional T cells and altered soluble immune factors in the cervicovaginal tract.The Journal of clinical investigation · 2025Observational
- Innate lymphoid cells in HIV pathogenesis and in the human female genital tract.Current opinion in HIV and AIDS · 2025Review
- Understanding the Associations of Urogenital Microbiomes With Fertility and In Vitro Fertilization.American journal of reproductive immunology (New York, N.Y. : 1989) · 2025Review
- Association between changes in genital immune markers and vaginal microbiome transitions in bacterial vaginosis.Scientific reports · 2025Article
- Enhanced and sustained biodistribution of HIV-1 neutralizing antibody VRC01LS in human genital and rectal mucosa.Nature communications · 2024Article
- Vaginal lactobacilli produce anti-inflammatory β-carboline compounds.Cell host & microbe · 2024Article
- Article
- Nonoptimal bacteria species induce neutrophil-driven inflammation and barrier disruption in the female genital tract.Mucosal immunology · 2023Article
- Vaginal epithelial dysfunction is mediated by the microbiome, metabolome, and mTOR signaling.Cell reports · 2023Article
- Comparative analysis of vaginal microbiota sampling using menstrual cups and high vaginal swabs in pregnant women living with HIV-1 infection.Frontiers in cellular and infection microbiology · 2023Article
- Female reproductive health impacts of Long COVID and associated illnesses including ME/CFS, POTS, and connective tissue disorders: a literature review.Frontiers in rehabilitation sciences · 2023Review
Corrections and comments
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Authors and funding
20 authors at 7 institutions in 4 countries.
Elizabeth H ByrneRagon Institute of Massachusetts General Hospital (MGH), Massachusetts Institute of Technology (MIT), and Harvard, Cambridge, MA, United States.
Mara FarcasanuRagon Institute of Massachusetts General Hospital (MGH), Massachusetts Institute of Technology (MIT), and Harvard, Cambridge, MA, United States.
Seth M BloomRagon Institute of Massachusetts General Hospital (MGH), Massachusetts Institute of Technology (MIT), and Harvard, Cambridge, MA, United States.
Nondumiso XuluHIV Pathogenesis Programme (HPP), The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.
Jiawu XuRagon Institute of Massachusetts General Hospital (MGH), Massachusetts Institute of Technology (MIT), and Harvard, Cambridge, MA, United States.
Barry L HykesDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, United States.
Nomfuneko A MafundaRagon Institute of Massachusetts General Hospital (MGH), Massachusetts Institute of Technology (MIT), and Harvard, Cambridge, MA, United States.
Matthew R HaywardRagon Institute of Massachusetts General Hospital (MGH), Massachusetts Institute of Technology (MIT), and Harvard, Cambridge, MA, United States.
Mary DongRagon Institute of Massachusetts General Hospital (MGH), Massachusetts Institute of Technology (MIT), and Harvard, Cambridge, MA, United States.
Krista L DongRagon Institute of Massachusetts General Hospital (MGH), Massachusetts Institute of Technology (MIT), and Harvard, Cambridge, MA, United States.
Thandeka GumbiFemales Rising Through Education, Support, and Health (FRESH), Durban, South Africa.
Fransisca Xolisile CeasarFemales Rising Through Education, Support, and Health (FRESH), Durban, South Africa.
Nasreen IsmailHIV Pathogenesis Programme (HPP), The Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.
Thumbi Ndung'uRagon Institute of Massachusetts General Hospital (MGH), Massachusetts Institute of Technology (MIT), and Harvard, Cambridge, MA, United States.
Christina GosmannRagon Institute of Massachusetts General Hospital (MGH), Massachusetts Institute of Technology (MIT), and Harvard, Cambridge, MA, United States.
Musie S GhebremichaelRagon Institute of Massachusetts General Hospital (MGH), Massachusetts Institute of Technology (MIT), and Harvard, Cambridge, MA, United States.
Scott A HandleyDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, United States.
Caroline M MitchellRagon Institute of Massachusetts General Hospital (MGH), Massachusetts Institute of Technology (MIT), and Harvard, Cambridge, MA, United States.
Alexandra-Chloé VillaniDepartment of Medicine, Harvard Medical School, Boston, MA, United States.
Douglas S KwonRagon Institute of Massachusetts General Hospital (MGH), Massachusetts Institute of Technology (MIT), and Harvard, Cambridge, MA, United States.
Ragon Institute of MGH, MIT and Harvard · USHarvard University · USMassachusetts General Hospital · USHealth Systems Trust · ZAUniversity of KwaZulu-Natal · ZAWashington University in St. Louis · USBroad Institute · US
Funding
The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI RAJESH T GANDHI · 2004 to 2026
$94.4MMedical Scientist Training ProgramT32GM007753 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WALENSKY, LOREN DAVID · 1985 to 2021
$50.0MMultidisciplinary HIV Training ProgramT32AI007387 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Daniel R. Kuritzkes · 1990 to 2026
$8.8MInflammation and the vaginal metagenome in HIV acquisitionR01AI111918 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI KWON, DOUGLAS, VIRGIN, HERBERT W · 2014 to 2017
$2.5MNIAID NIH HHS P30 AI060354NIAID NIH HHS R01 AI111918NIAID NIH HHS T32 AI007387NIGMS NIH HHS T32 GM007753
Abstract
The microbiome of the female genital tract (FGT) is closely linked to reproductive health outcomes. Diverse, anaerobe-dominated communities with low
Indexed as
HIV InfectionsMicrobiotaPremature BirthAntigen-Presenting CellsFemaleHormonal ContraceptionHumansInfant, NewbornInflammationPregnancyVaginafemale genital tractHIVhormonal contraceptionhost-microbiome interactioninflammationmicrobiomemucosal immunology
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.