Evidence map›Paper›PMID 34604102›Full record

ArticleFrontiers in cellular and infection microbiology2021

Taxonomic and Functional Dysregulation in Salivary Microbiomes During Oral Carcinogenesis.

Jiung-Wen Chen, Jer-Horng Wu, Wei-Fan Chiang, Yuh-Ling Chen, Wei-Sheng Wu, Li-Wha Wu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jiung-Wen ChenDepartment of Environmental Engineering, National Cheng Kung University, Tainan, Taiwan.
Jer-Horng WuDepartment of Environmental Engineering, National Cheng Kung University, Tainan, Taiwan.
Wei-Fan ChiangDepartment of Oral & Maxillofacial Surgery, Chi-Mei Medical Center, Liouying, Taiwan.
Yuh-Ling ChenInstitute of Oral Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Wei-Sheng WuDepartment of Electrical Engineering, National Cheng Kung University, Tainan, Taiwan.
Li-Wha WuInstitute of Molecular Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
National Cheng Kung University · TWChi Mei Medical Center · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exploring microbial community compositions in humans with healthy versus diseased states is crucial to understand the microbe-host interplay associated with the disease progression. Although the relationship between oral cancer and microbiome was previously established, it remained controversial, and yet the ecological characteristics and their responses to oral carcinogenesis have not been well studied. Here, using the bacterial 16S rRNA gene amplicon sequencing along with the

Indexed as

MicrobiotaCarcinogenesisDysbiosisHumansPhylogenyRNA, Ribosomal, 16SRNA, Ribosomal, 16Smachine learningmicrobiome dysbiosisoral canceroral verrucous hyperplasiasaliva

Identifiers

PMID34604102
PMCPMC8482814
OpenAlexW3199482318

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.